A9736

A-438079 hydrochloride hydrate

≥98% (HPLC)

• 동의어(들): 3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methyl pyridine hydrochloride hydrate
• 실험식(Hill 표기법): C₁₃H₉Cl₂N₅·HCl · xH₂O
• CAS Number: 899431-18-6
• Molecular Weight: 342.61 (anhydrous basis)
• MDL number: MFCD17215929
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329771058
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 저장 조건: desiccated
• 색상: white to beige
• solubility: DMSO: 20 mg/mL, clear
• 주관자: Abbott
• 저장 온도: 2-8°C
• SMILES string: O.Cl.Clc1cccc(c1Cl)-c2nnnn2Cc3cccnc3
• InChI: 1S/C13H9Cl2N5.ClH.H2O/c14-11-5-1-4-10(12(11)15)13-17-18-19-20(13)8-9-3-2-6-16-7-9;;/h1-7H,8H2;1H;1H2
• InChI key: ZHFJJBAKSROKNO-UHFFFAOYSA-N

설명

애플리케이션

A-438079 hydrochloride hydrate has been used to determine its inhibitory effect on purinergic receptors. It has also been used to check its inhibitory effects on macrophages.

생화학적/생리학적 작용

A-438079 hydrochloride hydrate is a selective P2X7 purinoceptor antagonist

A-438079 hydrochloride hydrate is a selective P2X7 purinoceptor antagonist in both human and rat with minimal activity at 75 different G-protein-coupled receptors, enzymes, transporters, and ion channels tested.

특징 및 장점

This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable