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Merck
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주요 문서

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SML0360

Sigma-Aldrich

TAK-715

≥98% (HPLC)

동의어(들):

N-(4-(2-Ethyl-4-(3-methylphenyl)-1,3-thiazol-5-yl)-2-pyridyl)benzamide

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모든 사진(1)

About This Item

실험식(Hill 표기법):
C24H21N3OS
CAS Number:
303162-79-0
Molecular Weight:
399.51
MDL number:
MFCD17012805
UNSPSC 코드:
12352200
PubChem Substance ID:
329825362
NACRES:
NA.77

Quality Level

100

분석

≥98% (HPLC)

양식

powder

색상

faintly yellow to dark yellow

solubility

DMSO: >15 mg/mL

저장 온도

2-8°C

SMILES string

CCc1nc(-c2cccc(C)c2)c(s1)-c3ccnc(NC(=O)c4ccccc4)c3

InChI

1S/C24H21N3OS/c1-3-21-27-22(18-11-7-8-16(2)14-18)23(29-21)19-12-13-25-20(15-19)26-24(28)17-9-5-4-6-10-17/h4-15H,3H2,1-2H3,(H,25,26,28)

InChI key

HEKAIDKUDLCBRU-UHFFFAOYSA-N

유전자 정보

human ... MAPK14(1432)

생화학적/생리학적 작용

TAK-715 is a potent p38 inhibitor that also inhibits CKId/e (casein kinase Id/e), known activator of Wnt/β-catenin signaling.

특징 및 장점

This compound is featured on the MAPKs page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

픽토그램

Exclamation mark
GHS07

신호어

Warning

유해 및 위험 성명서

H302,H319

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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시험 성적서(COA)

Lot/Batch Number
052M4622V

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문서

MAPKs

The mitogen-activated protein kinase (MAPK) family consists of both stress activated (SAPK) and mitogen-activated (MAPK) protein kinases. They form a network of signal transduction cascades that mediate cellular responses to a diverse range of stimuli, including growth factors, chemical or osmotic stress, irradiation, bacterial infection and proinflammatory cytokines.

자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..

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