모든 사진(1)
About This Item
실험식(Hill 표기법):
C22H20N4
CAS Number:
Molecular Weight:
340.42
MDL number:
UNSPSC 코드:
12352200
PubChem Substance ID:
NACRES:
NA.77
추천 제품
분석
≥98% (HPLC)
양식
powder
색상
white to beige
solubility
DMSO: ≥20 mg/mL
저장 온도
room temp
SMILES string
C(Nc1nc(NCc2ccccc2)c3ccccc3n1)c4ccccc4
InChI
1S/C22H20N4/c1-3-9-17(10-4-1)15-23-21-19-13-7-8-14-20(19)25-22(26-21)24-16-18-11-5-2-6-12-18/h1-14H,15-16H2,(H2,23,24,25,26)
InChI key
QAIMUUJJAJBPCL-UHFFFAOYSA-N
관련 카테고리
애플리케이션
HeLa cells were treated with DBeQ and the effects on in vivo ubiquitination and protein dislocation were studied by live cell imaging.
생화학적/생리학적 작용
ATPase p97 inhibitor.
DBeQ is a potent and specific inhibitor of ATPase p97, an integral component of the ubiquitin-fusion degradation (UFD) pathway. DBeQ inhibits the degradation of ubiquitinated proteins, the endoplasmic reticulum-associated degradation pathway, and autophagosome maturation. The compound also potently inhibits cellular proliferation and induces caspase 3/7 activity and apoptosis.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
이미 열람한 고객
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Journal of cellular and molecular medicine, 20(1), 58-70 (2015-10-16)
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문서
We presents an article on Autophagy in Cancer Promotes Therapeutic Resistance
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