SMB01019

Amorfrutin A

≥90% (LC/MS-ELSD)

• 동의어(들): 2-hydroxy-4-methoxy-3-(3-methylbut-2-enyl)-6-(2-phenylethyl)benzoic acid, 3-hydroxy-4-isopentenyl-5-methoxybibenzyl-2-carboxylic acid
• 실험식(Hill 표기법): C₂₁H₂₄O₄
• CAS Number: 80489-90-3
• Molecular Weight: 340.41
• MDL number: MFCD23703108
• UNSPSC 코드: 12352205
• NACRES: NA.25

속성

• 생물학적 소스: plant
• 분석: ≥90% (LC/MS-ELSD)
• 양식: solid
• 분자량: 340.41
• solubility: water: slightly soluble
• 응용 분야: metabolomics; vitamins, nutraceuticals, and natural products
• 저장 온도: −20°C
• SMILES string: O(C)c1c(c(c(c(c1)CCc2ccccc2)C(=O)O)O)CC=C(C)C
• InChI: 1S/C21H24O4/c1-14(2)9-12-17-18(25-3)13-16(19(20(17)22)21(23)24)11-10-15-7-5-4-6-8-15/h4-9,13,22H,10-12H2,1-3H3,(H,23,24)
• InChI key: CTNFTPUIYFUXBE-UHFFFAOYSA-N

설명

일반 설명

Amorfrutin A is a stilbenoid compound commonly present in plants like Glycyrrhiza foetida, Glycyrrhiza acanthocarpa, Cajanus cajan, and Amorpha fruticosa. Current research indicates that this naturally occurring metabolite possesses diverse biological activities, including anti-inflammatory, anticancer, antidiabetic, and antimicrobial properties.

애플리케이션

It is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

생화학적/생리학적 작용

According to the existing research, Amorfrutin-A demonstrated its ability to inhibit NF-κB activity, a pivotal regulator of genes governing a wide range of cellular functions, such as immune responses, apoptosis, tumor growth, and tissue development. Furthermore, it exhibits anti-inflammatory properties in colon cells by interacting with the nuclear receptor PPARγ, resulting in the reduced expression and secretion of inflammatory mediators. This suggests its potential for treating conditions like inflammatory bowel diseases. Additionally, it also exhibited antidiabetic activity through binding to and activating the nuclear receptor PPARγ.

특징 및 장점

• High quality compound suitable for multiple research applications
• Compatible with HPLC and mass spectrometry techniques

기타 정보

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안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable