SAB5600015

Anti-Acetyl-Histone H3 (Lys56) antibody, Rabbit monoclonal

recombinant, expressed in HEK 293 cells, clone RM179, purified immunoglobulin

• 동의어(들): H3K56ac, Histone H3 (acetyl K56)
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 재조합: expressed in HEK 293 cells
• Quality Level: 100
• 항체 형태: purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: RM179, monoclonal; recombinant monoclonal
• 양식: buffered aqueous glycerol solution
• 종 반응성: human
• 농도: ~1 mg/mL
• 기술: ELISA: 0.5-1 μg/mL; immunocytochemistry: 0.5-2 μg/mL; immunohistochemistry: 1 ug/mL – 10 ug/mL; western blot: 1-2 μg/mL
• 동형: IgG
• NCBI 수납 번호: 8350
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: acetylation (Lys56)
• 유전자 정보: human ... H3C1(8350)

설명

일반 설명

Mammals contain three main classes of histone H3 variants: the replicative histones (H3.1 and H3.2), the replacement histone (H3.3) and the centromeric histone (Cenp-A). Histone H3 is located on human chromosome 6p22.

특이성

This antibody reacts to Histone H3 acetylated at Lysine 56 (K56ac). No cross reactivity with other acetylated Lysines in histone H3.

면역원

Synthetic peptide corresponding to the Acetyl-Histone H3 (Lys56)

생화학적/생리학적 작용

Histone proteins are basic building blocks of chromatin. Histone H3 K27M mutations in adult cerebellar high-grade gliomas. It controls protein-protein interactions to induce binding of trans-acting factors that drive chromatin condensation.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

Solution in phosphate buffered saline containing 50% glycerol, 1% BSA and 0.09% sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable