07-595

Anti-acetyl-Histone H4 (Lys12) Antibody

serum, Upstate^®

• 동의어(들): H4K12Ac, Histone H4 (acetyl K12)
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 항체 형태: serum
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 종 반응성: Saccharomyces cerevisiae, human
• 제조업체/상표: Upstate^®
• 기술: ChIP: suitable (ChIP-seq); dot blot: suitable; western blot: suitable
• 동형: IgG
• NCBI 수납 번호: NM_175054
• UniProt 수납 번호: P62805; Q6DRA9
• 배송 상태: dry ice
• 타겟 번역 후 변형: acetylation (Lys12)
• 유전자 정보: human ... HIST2H4B(554313)

설명

일반 설명

Histone H4 is one of the 5 main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N terminal tail H4 is involved with the structure of the nucleosomes of the ′beads on a string′ structure.

Acetylation of histone H4 occurs at several different lysine positions in the histone tail and is performed by a family of enzymes known as Histone Acetyl Transferases (HATs).

특이성

Broad species cross-reactivity expected

Recognizes Histone H4 acetylated on lysine 12.

면역원

peptide containing the sequence (LG_AcKGG) corresponding to lysine 12 acetylation of yeast Histone H4.

애플리케이션

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Histones

Use Anti-acetyl-Histone H4 (Lys12) Antibody (Rabbit Polyclonal Antibody) validated in ChIP, DB, WB, ChIP-seq to detect acetyl-Histone H4 (Lys12) also known as H4K12Ac, Histone H4 (acetyl K12).

품질

routinely evaluated by immunoblot on acid extracted proteins from HeLa cells

표적 설명

10 kDa

물리적 형태

Depleted rabbit antiserum in 30% glycerol, 0.07M Tris-glycine, pH 7.4, 0.105 M NaCl, 0.035% sodium azide as a preservative.

Immunodepleted Serum

저장 및 안정성

Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

분석 메모

Control
Acid extracted proteins from HeLa cells treated with sodium butyrate

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

법적 정보

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1