SAB5500153

Anti-NRAS Antibody

rabbit monoclonal, SP174

• 동의어(들): Anti-ALPS4, Anti-CMNS, Anti-KRAS, Anti-N-ras, Anti-NCMS, Anti-NRAS1, Anti-NS6
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 제품명: Anti-N-RAS antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP174, affinity isolated antibody
• 생물학적 소스: rabbit
• Quality Level: 100
• 재조합: expressed in proprietary host
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: SP174, monoclonal
• 종 반응성: human (tested)
• 기술: immunoblotting: 1:400; immunohistochemistry: 1:100
• 동형: IgG
• UniProt 수납 번호: P01111
• 배송 상태: wet ice
• 저장 온도: 2-8°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... NRAS(4893)

설명

일반 설명

GTPase N-Ras or N-Ras is a guanine-nucleotide binding protein. Receptor tyrosine kinases and G-protein-coupled receptors activate Ras, which then stimulates the MAPK signal pathway. Point mutations (Q61R) in Ras prevent the GAP-mediated inhibition of the MAPK pathway in certain cancers such as lung carcinoma and melanoma. Abnormal MAPK signaling may lead to uncontrolled cell proliferation, resistance to both apoptosis and cancer therapy.

면역원

Synthetic peptide of human N-Ras protein containing N-Ras (Q61R) point mutation.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable