추천 제품
생물학적 소스
rabbit
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
양식
buffered aqueous solution
분자량
antigen 72 kDa
종 반응성
human, mouse, rat
농도
~1 mg/mL
기술
ELISA: 1:10000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
phosphorylation (pTyr348)
유전자 정보
human ... SYK(6850)
일반 설명
Spleen tyrosine kinase (SYK) is a member of the non-receptor tyrosine kinase family. It is usually expressed in epithelial breast tissues and hematopoietic cells.SYK is mapped to human chromosome 9q22.
면역원
The antiserum was produced against synthesized peptide derived from human SYK around the phosphorylation site of Tyr348.
Immunogen Range: 314-363
Immunogen Range: 314-363
생화학적/생리학적 작용
Spleen tyrosine kinase (SYK), as a tumor suppressor gene helps to prevent the development and metastasis of breast cancer cells.It participates in B-cell receptor signaling.This protein helps to phosphorylate the α-tubulin subunits of microtubules.
특징 및 장점
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
물리적 형태
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
Syk: a new player in the field of breast cancer
Stewart ZA and Pietenpol JA
Breast Cancer Research, 3(1), 5-7 (2001)
Novel SYK gene variations and changes in binding sites of miRs in breast cancer patients
Faryal R, et al.
Cancer Biomarkers : Section A of Disease Markers, 16(3), 319-326 (2016)
Genomic and expression profiling identifies the B-cell associated tyrosine kinase Syk as a possible therapeutic target in mantle cell lymphoma
Rinaldi A, et al.
British Journal of Haematology, 132(3), 303-316 (2006)
Jiancheng Hu et al.
Journal of immunology (Baltimore, Md. : 1950), 193(1), 85-95 (2014-06-04)
Lysophospholipids have emerged as biologically important chemoattractants capable of directing lymphocyte development, trafficking, and localization. Lysophosphatidic acid (LPA) is a major lysophospholipid found systemically, and its levels are elevated in certain pathological settings, such as cancer and infections. In this
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