SAB4503839

Anti-phospho-SYK (pTyr⁵²⁵) antibody produced in rabbit

affinity isolated antibody

• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 양식: buffered aqueous solution
• 분자량: antigen 72 kDa
• 종 반응성: mouse, rat, human
• 농도: ~1 mg/mL
• 기술: ELISA: 1:20000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI 수납 번호: P43405
• UniProt 수납 번호: P43405
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: phosphorylation (pTyr525)
• 유전자 정보: human ... SYK(6850)

설명

일반 설명

Spleen tyrosine kinase (SYK) is a member of the non-receptor tyrosine kinase family. It is usually expressed in epithelial breast tissues and hematopoietic cells. SYK is mapped to human chromosome 9q22.

면역원

The antiserum was produced against synthesized peptide derived from human SYK around the phosphorylation site of Tyr525.

Immunogen Range: 491-540

애플리케이션

Anti-phospho-SYK (pTyr525) antibody has been used in immunohistochemistry.

생화학적/생리학적 작용

Spleen tyrosine kinase (SYK), as a tumor suppressor gene helps to prevent the development and metastasis of breast cancer cells. It participates in B-cell receptor signaling. This protein helps to phosphorylate the α-tubulin subunits of microtubules.

특징 및 장점

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물리적 형태

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable