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Merck
모든 사진(2)

주요 문서

SAB4502354

Sigma-Aldrich

Anti-PKC α antibody produced in rabbit

affinity isolated antibody

동의어(들):

KPCA, PKC III, PKC-α, PKC-A, kinase PKC-α

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

rabbit

결합

unconjugated

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

양식

buffered aqueous solution

분자량

antigen 76 kDa

종 반응성

human, mouse, rat

농도

~1 mg/mL

기술

ELISA: 1:1000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

NCBI 수납 번호

UniProt 수납 번호

배송 상태

wet ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... PRKCA(5578)

일반 설명

Anti-PKC α Antibody detects endogenous levels of total PKC α protein.
PKC α (protein kinase C α) gene is mapped to 17q24.2. PKC α is expressed in heart, liver, brain and epithelium.

면역원

The antiserum was produced against synthesized peptide derived from human PKC alpha.

Immunogen Range: 606-655

생화학적/생리학적 작용

PKC (protein kinase C) is known to mediate different cellular processes, such as transcription regulation, cell signaling, cell proliferation, immune responses and apoptosis. While PKC is also associated with the learning ability. Abnormal cell signaling induced by PKC is often observed in cancer. PKC α (protein kinase C α) being one of the isozymes of the PKC family, it catalyzes the phosphorylation of substrates with many peptides.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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문서 라이브러리 방문

Distinct structural mechanisms determine substrate affinity and kinase activity of protein kinase C?.
Lee S
The Journal of Biological Chemistry, 292(39), 16300-16309 (2017)
Shared genetic variants between serum levels of high-density lipoprotein cholesterol and wheezing in a cohort of children from Cyprus
Panayiotis K. Yiallouros
Italian Journal of Pediatrics, 42: 67, 1-9 (2016)
Polyphenol compounds and PKC signaling.
Das J
Biochimica et Biophysica Acta, 1860(10), 2107-2121 (2016)
Md Sajid Ghufran et al.
Cell biology and toxicology, 35(1), 67-80 (2018-07-08)
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