추천 제품
생물학적 소스
rabbit
Quality Level
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
양식
buffered aqueous solution
종 반응성
human
기술
immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable
NCBI 수납 번호
UniProt 수납 번호
배송 상태
dry ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... SLC39A8(64116)
일반 설명
Solute carrier family 39 member 8 (SLC39A8), also known as zinc- and iron-related protein 8 (ZIP8), is a plasma membrane transporter protein. It is part of the solute carrier gene superfamily. The gene encoding SLC39A8 is localized on human chromosome 4q24.
면역원
ZIP8 antibody was raised against a 18 amino acid peptide near the carboxy terminus of human ZIP8.
애플리케이션
Anti-ZIP8 antibody produced in rabbit has been used in immunocytochemistry.
생화학적/생리학적 작용
Solute carrier family 39 member 8 (SLC39A8) co-transports divalent metal cations like cadmium, zinc, manganese and iron. It has a crucial role in the cellular uptake of cadmium. The protein is a target of nuclear-factor κB (NF-κB) and has a role in pro-inflammatory responses.
특징 및 장점
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
결합
The action of this antibody can be blocked using blocking peptide SBP3500598.
물리적 형태
Supplied in PBS with 0.02% sodium azide.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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관련 제품
Storage Class Code
10 - Combustible liquids
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
Autosomal-Recessive Intellectual Disability with Cerebellar Atrophy Syndrome Caused by Mutation of the Manganese and Zinc Transporter Gene SLC39A8.
Boycott KM
American Journal of Human Genetics (2015)
ZIP8 regulates host defense through zinc-mediated inhibition of NF-?B.
Liu MJ
Cell Reports (2013)
A blood pressure-associated variant of the SLC39A8 gene influences cellular cadmium accumulation and toxicity.
Zhang R
Human Molecular Genetics (2016)
Advances in the genetics of schizophrenia: toward a network and pathway view for drug discovery: Advances in the genetics of schizophrenia
David A
The New York State Dental Journal (2016)
Cellular localization and developmental
changes of Zip8, Zip14 and transferrin
receptor 1 in the inner ear of rats
changes of Zip8, Zip14 and transferrin
receptor 1 in the inner ear of rats
Dalian Ding
Biometals: An International Journal on the Role of Metal Ions in Biology, Biochemistry, And Medicine (2014)
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