SAB3500343

Anti-Bax antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

• 동의어(들): Anti-Bax
• MDL number: MFCD00282585
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 결합: unconjugated
• 항체 형태: IgG fraction of antiserum
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 양식: buffered aqueous solution
• 종 반응성: human
• 기술: immunocytochemistry: suitable; immunofluorescence: suitable; immunoprecipitation (IP): suitable; indirect ELISA: suitable; western blot: suitable
• NCBI 수납 번호: AAA03619
• UniProt 수납 번호: Q07812
• 배송 상태: dry ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... BAX(581)

설명

일반 설명

BCL2 associated X, apoptosis regulator (BAX) is a proapoptotic protein of the B-cell lymphoma 2 (BCL2) protein family. The gene encoding it is localized on human chromosome 19q13.33.

면역원

Bax antibody was raised against a peptide corresponding to 16 amino acids near the amino-terminus of human Bax.

애플리케이션

Anti-Bax antibody produced in rabbit has been used in Western blotting.

생화학적/생리학적 작용

BCL2 associated X, apoptosis regulator (BAX) forms a heterodimer with B-cell lymphoma 2 (BCL2) and functions as an apoptotic activator. BAX interacts with and increases the opening of the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in the mitochondrial membrane potential and the release of cytochrome c. The expression of BAX gene is regulated by the tumor suppressor p53 and BAX has been shown to be involved in p53-mediated apoptosis.

특징 및 장점

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결합

The action of this antibody can be blocked using blocking peptide SBP3500343.

물리적 형태

Supplied in PBS with 0.02% sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable