S1129

Succinyl coenzyme A sodium salt

≥85%

• 동의어(들): Succinyl CoA sodium salt
• 실험식(Hill 표기법): C₂₅H₄₀N₇O₁₉P₃S
• CAS Number: 108347-97-3
• Molecular Weight: 867.61
• UNSPSC 코드: 41106305
• PubChem Substance ID: 24899460
• NACRES: NA.51

속성

• Quality Level: 200
• 분석: ≥85%
• 양식: powder
• solubility: water: 50 mg/mL, clear, colorless
• 저장 온도: −20°C
• SMILES string: [Na+].[Na+].CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)([O-])=O)n2cnc3c(N)ncnc23)C(O)C(=O)NCCC(=O)NCCSC(=O)CCC([O-])=O
• InChI: 1S/C25H40N7O19P3S/c1-25(2,20(38)23(39)28-6-5-14(33)27-7-8-55-16(36)4-3-15(34)35)10-48-54(45,46)51-53(43,44)47-9-13-19(50-52(40,41)42)18(37)24(49-13)32-12-31-17-21(26)29-11-30-22(17)32/h11-13,18-20,24,37-38H,3-10H2,1-2H3,(H,27,33)(H,28,39)(H,34,35)(H,43,44)(H,45,46)(H2,26,29,30)(H2,40,41,42)/p-2/t13-,18-,19-,20?,24-/m1/s1
• InChI key: VNOYUJKHFWYWIR-FZEDXVDRSA-L

설명

애플리케이션

Succinyl coenzyme A sodium salt has been used:

• for the nonenzymatic succinylation of lysine in vitro,
• as a substrate for adipic acid biosynthesis in recombinant E. coli
• in isocitrate dehydrogenase (ICDH) treatment for the succinylation of proteins
• as a substrate to study the specificity and kinetics of enzymes such as acetate:succinate CoA-transferase and 5-aminolevulinate synthase (ALA synthase)

생화학적/생리학적 작용

Succinyl CoA is an intermediate in the citric acid cycle. It is formed by α-ketoglutarate dehydrogenase by the decarboxylation of α-ketoglutarate. Succinyl CoA is also formed from propionyl CoA during the β-oxidation of odd-chain fatty acids. Succinyl CoA serves as a precursor in heme synthesis. It is also required for the oxidation of ketone bodies.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315,H319,H335
• 예방조치 성명서: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves