RAB0564

Mouse Tnfsf4 / Tumor Necrosis Factor Ligand Superfamily Member 4 ELISA Kit

for serum, plasma and cell culture supernatants

• UNSPSC 코드: 41116158
• NACRES: NA.84

속성

• 종 반응성: mouse
• 포장: kit of 96 wells (12 strips x 8 wells)
• 기술: ELISA: suitable
• 입력: sample type serum; sample type plasma; sample type cell culture supernatant(s)
• assay range: inter-assay cv: <10%; intra-assay cv: <12%; sensitivity: 30 pg/mL
• 검출 방법: colorimetric
• 배송 상태: wet ice
• 저장 온도: −20°C
• 유전자 정보: mouse ... Tnfsf4(22164)

설명

일반 설명

This ELISA antibody pair detects mouse TNFSF4/OX40.

애플리케이션

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

생화학적/생리학적 작용

Tumor necrosis factor (TNF) superfamily member 4 (Tnfsf4) signals specifically through the OX40 receptor, which is expressed primarily on CD4⁺T cells but also on certain activated CD8⁺T cells. Tnfsf4 acts as a costimulatory signal, which is essential for a productive interaction between antigen presenting cells and their target T-cells. It enhances cell proliferation and survival and increases expression of regulated on activation, normal T cell expressed and secreted (RANTES) or chemokine ligand 5 (CCL5), interleukins-2 and -3 and interferon γ (IFNg). Tnfsf4 signaling plays an important role in immuno-regulatory communication and immune-tolerance. Polymorphisms in the TNFSF4 gene leads to the development of autoimmune thyroid diseases (AITDs), rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) and systemic sclerosis (SSc).

기타 정보

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

키트 구성품 역시 별도로 이용 가능함

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• RABSTOP3 ELISA Stop Solution (Item I)
• RABELADA ELISA 1X Assay/Sample Diluent Buffer A (Item D1)
• RABELADB ELISA 5X Assay/Sample Diluent Buffer B (Item E1)
• RABWASH4 20X Wash Buffer (Item B)

안전성 정보

• 픽토그램: GHS05
• 신호어: Warning
• 유해 및 위험 성명서: H290
• 예방조치 성명서: P234 - P390
• Hazard Classifications: Met. Corr. 1
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable