추천 제품
종 반응성
human
포장
kit of 96 wells (12 strips x 8 wells)
기술
ELISA: suitable
capture ELISA: suitable
입력
sample type serum
sample type cell culture supernatant(s)
sample type plasma
sample type urine
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 1 pg/mL
standard curve range: 0.55-400 pg/mL
검출 방법
colorimetric
배송 상태
wet ice
저장 온도
−20°C
유전자 정보
human ... TNFRSF1A(7132)
일반 설명
The Human sTNF RI (soluble tumor necrosis factor receptor I) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme- linked immunosorbent assay for the quantitative measurement of human sTNF RI in serum, plasma, cell culture supernatants and urine.
면역원
Recombinant Human TNF RI
애플리케이션
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
생화학적/생리학적 작용
Tumour necrosis factor (TNF) receptor superfamily member 1A is a type I single transmembrane glycoprotein. Signal transduction mediated by binding of TNFα regulates inflammatory, immune responses and apoptotic pathway. TNF receptor 1 is implicated in the end-stage renal disease and associated mortality. Mutations in TNF receptor 1 causes autosomal dominant tumor necrosis factor receptor-associated periodic syndrome (TRAPS). Polymorphism in TNF receptor 1 causes multiple sclerosis.
기타 정보
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
신호어
Warning
유해 및 위험 성명서
예방조치 성명서
Hazard Classifications
Met. Corr. 1
Storage Class Code
8A - Combustible corrosive hazardous materials
TNF receptor 1 genetic risk mirrors outcome of anti-TNF therapy in multiple sclerosis
Gregory AP, et al.
Nature, 488(7412), 508-511 (2012)
A novel TNFRSF1A gene mutation in a patient with tumor necrosis factor receptor-associated periodic syndrome
Khabazi A, et al.
Hematology/oncology and Stem Cell Therapy, 11(3), 175-177 (2018)
Circulating TNF receptors 1 and 2 predict mortality in patients with end-stage renal disease undergoing dialysis
Gohda T, et al.
Scientific Reports, 7, 43520-43520 (2017)
Kazuo Kubota et al.
Journal of clinical immunology, 34(5), 584-593 (2014-04-25)
To investigate clinical presentation, genetic background and cytokine profile of Japanese sporadic cases of periodic fever, aphthous stomatitis, pharyngitis and adenitis (PFAPA) syndrome. Nine PFAPA syndrome patients were recruited. DNA sequence analysis of auto inflammatory disorder susceptibility genes, MEFV, MVK
Anil K Taneja et al.
International journal of cardiology, 175(2), 253-260 (2014-06-01)
Heart failure activates neurohormones, and elevated levels of brain natriuretic peptide (BNP) are associated with adverse outcomes. The SENIORS trial showed that nebivolol, a highly selective beta-1 antagonist with vasodilating properties, reduced the composite outcome of all cause mortality or
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