추천 제품
종 반응성
mouse
포장
kit of 96 wells (12 strips x 8 wells)
기술
ELISA: suitable
capture ELISA: suitable
입력
sample type serum
sample type cell culture supernatant(s)
sample type plasma
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 5 pg/mL
standard curve range: 4.1-1000 pg/mL
검출 방법
colorimetric
배송 상태
wet ice
저장 온도
−20°C
유전자 정보
mouse ... Ccl19(24047)
일반 설명
C-C motif chemokine ligand 19 (CCL19), also known as macrophage inflammatory protein (MIP)-3β, is encoded by the gene mapped to human chromosome 9. The encoded protein is specifically expressed in lymphoid tissues.
The Mouse MIP-3-β (Macrophage Inflammatory Protein 3 β) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of mouse MIP-3- β in serum, plasma, cell culture supernatants and urine.
면역원
Recombinant Mouse MIP-3 β
애플리케이션
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
생화학적/생리학적 작용
C-C motif chemokine ligand 19 (CCL19) acts as a chemoattractant for T and B lymphocytes, dendritic cells, macrophage progenitor cells and natural killer cells. Therefore, this protein might play an essential role in migration of T cells in the thymus and transfer of T and B cells to secondary lymphoid organs. Overexpression of MIP-3 β (macrophage inflammatory protein-3β)/ C-C motif chemokine ligand 19 (CCL19) leads to pulmonary sarcoidosis.
기타 정보
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
신호어
Warning
유해 및 위험 성명서
예방조치 성명서
Hazard Classifications
Met. Corr. 1
Storage Class Code
8B - Non-combustible corrosive hazardous materials
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
Expression of macrophage inflammatory protein-3 beta/CCL19 in pulmonary sarcoidosis.
American Journal of Respiratory and Critical Care Medicine, 167(12), 1695-1703 (2003)
CCL19 and CCL21 induce a potent proinflammatory differentiation program in licensed dendritic cells.
Immunity, 22(4), 493-505 (2005)
The CCR7 ligand elc (CCL19) is transcytosed in high endothelial venules and mediates T cell recruitment.
The Journal of Experimental Medicine, 193(9), 1105-1112 (2001)
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