P9797

Pyridostigmine bromide

• 동의어(들): 3-(Dimethylaminocarbonyloxy)-1-methylpyridinium bromide
• 실험식(Hill 표기법): C₉H₁₃BrN₂O₂
• CAS Number: 101-26-8
• Molecular Weight: 261.12
• EC Number: 202-929-9
• MDL number: MFCD00079283
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24277865
• NACRES: NA.77

속성

• 분석: ≥98% (HPLC)
• Quality Level: 100
• 양식: solid
• solubility: water: 100 mg/mL, clear to very slightly hazy, colorless
• 주관자: Valeant
• SMILES string: [Br-].CN(C)C(=O)Oc1ccc[n+](C)c1
• InChI: 1S/C9H13N2O2.BrH/c1-10(2)9(12)13-8-5-4-6-11(3)7-8;/h4-7H,1-3H3;1H/q+1;/p-1
• InChI key: VNYBTNPBYXSMOO-UHFFFAOYSA-M
• 유전자 정보: human ... ACHE(43)

설명

애플리케이션

Pyridostigmine bromide has been used as a cholinesterase inhibitor in mice, in florimetric assay for acetylcholine secretion and for measuring acetylcholine release from mice atrial tissue.

생화학적/생리학적 작용

Acetylcholinesterase inhibitor.

Pyridostigmine bromide inhibits acetylcholine esterase and is membrane impermeable. It is used as a preventive medicine in chemical warfare. Pyridostigmine bromide is a carbamate compound comprising quaternary amine structure. It displays low absorption at the gastrointestinal tract. Sustained release of pyridostigmine is recommended for improving its bioavailability in treating myasthenia gravis.

특징 및 장점

This compound was developed by Valeant. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

안전성 정보

• 픽토그램: GHS06
• 신호어: Danger
• 유해 및 위험 성명서: H300 + H310 + H330,H317
• 예방조치 성명서: P262 - P280 - P301 + P310 + P330 - P302 + P352 + P310 - P304 + P340 + P310
• Hazard Classifications: Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral - Skin Sens. 1
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges