추천 제품
생물학적 소스
rabbit
Quality Level
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
양식
lyophilized powder
종 반응성
mouse, rat, human
기술
immunohistochemistry: suitable
western blot: 1:200-1:500
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... NGFR(4804)
mouse ... Ngfr(18053)
rat ... Ngfr(24596)
특이성
Does not cross react with pro-BDNF, pro-NT-3, or mature NGF.
면역원
peptide corresponding to amino acid residues 84-104 of rat NGF (precursor). The sequence is identical in mouse and 16/21 residues identical in human.
물리적 형태
Lyophilized from phosphate buffered saline, pH 7.4, 1% BSA and <0.1% sodium azide
제조 메모
Reconstitute the lyophilized vial with 0.2 ml deionized water.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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신호어
Warning
유해 및 위험 성명서
예방조치 성명서
Hazard Classifications
Acute Tox. 4 Dermal - Aquatic Chronic 3
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
Comparison of nerve growth factor receptor binding models using heterodimeric muteins
Mehta HM et al
Journal of Neuroscience Research, doi: 10-doi: 10 (2012)
M Fahnestock et al.
Molecular and cellular neurosciences, 18(2), 210-220 (2001-08-25)
Nerve growth factor (NGF) is important for regulation, differentiation, and survival of peripheral and central nervous system neurons, including basal forebrain cholinergic neurons (BFCN) which degenerate in Alzheimer's disease (AD). Mature NGF protein is processed from a larger precursor, proNGF.
Death of injured neurons caused by the precursor of nerve growth factor.
Y-A Barde
Proceedings of the National Academy of Sciences of the United States of America, 101(16), 5703-5704 (2004-04-14)
Bai Lu
Neuron, 39(5), 735-738 (2003-09-02)
Neurotrophins are synthesized first as precursors, followed by maturation through proteolytic removal of the "pro" region. Since pro- and mature neurotrophins elicit opposite functional effects by differential interactions with Trks and p75 receptors, extracellular cleavage represents a new way to
Elahe Karimi et al.
Drug design, development and therapy, 13, 2513-2532 (2019-08-24)
Nowadays, the drug delivery system is important in the treatment of diseases. A polymeric nanoparticle modified by oleic acid (NPMO) as a Thymol (Thy) drug release system was synthesized from Thymbra spicata and its neurotrophic and angiogenic effects on rat's
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