P4498

Pravastatin sodium salt hydrate

≥98% (HPLC), powder

• 동의어(들): (βR, δR,1S,2S,6S,8S,8aR)-1,2,6,7,8,8a-Hexahydro-β, δ,6-trihydroxy-2-methyl-8[(2S)-2-methyl-1-oxobutoxyl]-1-naphthaleneheptanoic acid sodium hydrate, Eptastatin sodium salt hydrate
• 실험식(Hill 표기법): C₂₃H₃₅O₇Na · xH₂O
• CAS Number: 81131-70-6
• Molecular Weight: 446.51 (anhydrous basis)
• MDL number: MFCD00887601
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329820206
• NACRES: NA.77

속성

• 생물학적 소스: synthetic (organic)
• 분석: ≥98% (HPLC)
• 형태: powder
• 색상: white
• mp: 171.2-173 °C
• solubility: H₂O: >10 mg/mL
• 주관자: Bristol-Myers Squibb
• 저장 온도: 2-8°C
• SMILES string: [Na+].[H][C@@](O)(CC[C@H]1[C@@H](C)C=CC2=C[C@@H](O)C[C@H](OC(=O)[C@@H](C)CC)[C@]12[H])C[C@@H](O)CC([O-])=O
• InChI: 1S/C23H36O7.Na/c1-4-13(2)23(29)30-20-11-17(25)9-15-6-5-14(3)19(22(15)20)8-7-16(24)10-18(26)12-21(27)28;/h5-6,9,13-14,16-20,22,24-26H,4,7-8,10-12H2,1-3H3,(H,27,28);/q;+1/p-1/t13-,14-,16+,17+,18+,19-,20-,22-;/m0./s1
• InChI key: VWBQYTRBTXKKOG-IYNICTALSA-M
• 유전자 정보: human ... HMGCR(3156)

설명

일반 설명

Pravastatin sodium is an orally effective hypocholesterolaemic agent which is structurally similar to lovastatin and compactin.

애플리케이션

Pravastatin sodium salt hydrate has been used in the enzymatic method to measure mevalonic acid in serum.

생화학적/생리학적 작용

Pravastatin sodium is a competitive, water-soluble 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor.

Competitive, water-soluble 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor. Inhibits cholesterol synthesis in vivo (Ki ~1 nM).

특징 및 장점

This compound was developed by Bristol-Myers Squibb. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)