P2363

Protein Kinase G II from rat

>90% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf9 cells, solution

• 동의어(들): Protein Kinase, 3′,5′-Cyclic GMP Dependent from rat
• MDL number: MFCD03444648
• UNSPSC 코드: 41106305
• NACRES: NA.32

속성

• 재조합: expressed in baculovirus infected Sf9 cells
• Quality Level: 200
• 분석: >90% (SDS-PAGE)
• 양식: solution
• 특이 활성도: ~0.7 U/mg
• UniProt 수납 번호: Q64595
• 배송 상태: dry ice
• 저장 온도: −20°C
• 유전자 정보: rat ... Prkg2(25523)

설명

일반 설명

Protein kinase, cGMP-dependent, type II (PRKG2), also known as type II cGMP-dependent protein kinase (cGK), is encoded by the gene mapped to human chromosome 4q13.1–q21.1.

생화학적/생리학적 작용

Protein kinase, cGMP-dependent, type II (PRKG2) is implicated in the regulation of intestinal fluid balance in man. The encoded protein plays an essential role in proliferative to hypertrophic transition of growth plate chondrocytes during endochondral ossification. Loss of PRKG2 function is associated with the development of renal cysts, intellectual disability and speech defect. In rodent and bovine models, deletion of the gene leads to dwarfism.

단위 정의

One unit will phosphorylate one μmole of VASPtide (RRKVSKQE) per minute at pH 7.4

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable