추천 제품
생물학적 소스
rabbit
Quality Level
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
양식
lyophilized powder
종 반응성
rat
기술
western blot: 1:200 using rat heart membranes
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
유전자 정보
human ... KCNJ8(3764)
mouse ... Kcnj8(16523)
rat ... Kcnj8(25472)
특이성
Specific for KIR6.1; does not cross react with KIR6.2.
면역원
peptide, (C)KRNSMRRNNSMRRSN, corresponding to amino acid residues 382-396 of rat KIR6.1. This sequence has 15/16 residues identical in human, pig, rabbit, and mouse.
물리적 형태
Lyophilized from phosphate buffered saline containing 1% bovine serum albumin and 0.025% sodium azide.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
William C Cole et al.
Journal of cardiovascular electrophysiology, 14(1), 94-103 (2003-03-11)
ATP-sensitive potassium channels (K(ATP)) of vascular smooth muscle cells represent potential therapeutic targets for control of abnormal vascular contractility. The biophysical properties, regulation and pharmacology of these channels have received intense scrutiny during the past twenty years, however, the molecular
T Baukrowitz et al.
European journal of biochemistry, 267(19), 5842-5848 (2000-09-21)
The KATP channel is a heterooctamer composed of two different subunits, four inwardly rectifying K+ channel subunits, either Kir6. 1 or Kir6.2, and four sulfonylurea receptors (SUR), which belong to the family of ABC transporters. This unusual molecular architecture is
Mangala M Soundarapandian et al.
Journal of neurochemistry, 103(5), 1982-1988 (2007-09-22)
The Kir6.1 channels are a subtype of ATP-sensitive inwardly rectifying potassium (K(ATP)) channels that play an essential role in coupling the cell's metabolic events to electrical activity. In this study, we show that functional Kir6.1 channels are located at excitatory
Yang Yang et al.
The Journal of biological chemistry, 286(11), 9298-9307 (2011-01-11)
The vascular ATP-sensitive K(+) (K(ATP)) channel is targeted by a variety of vasoactive substances, playing an important role in vascular tone regulation. Our recent studies indicate that the vascular K(ATP) channel is inhibited in oxidative stress via S-glutathionylation. Here we
Maria Consiglia Trotta et al.
Frontiers in physiology, 9, 1475-1475 (2018-11-13)
The study explored the anti-hypertrophic effect of the melanocortin MC5R stimulation in H9c2 cardiac myocytes exposed to high glucose. This has been done by using α-MSH and selective MC5R agonists and assessing the expression of GLUT4 and GLUT1 transporters, miR-133
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