MSQC20

SILu^™Lite SigmaMAb Bevacizumab Monoclonal Antibody

recombinant, expressed in CHO cells

• 동의어(들): Mass spectrometry standard, Bevacizumab
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 재조합: expressed in CHO cells
• 분석: ≥90% (SDS-PAGE)
• 형태: solid
• 적합성: suitable for mass spectrometry
• 배송 상태: wet ice
• 저장 온도: −20°C

설명

일반 설명

SigmaMAb Bevacizumab (MSQC20) was designed to be a standard for the analysis of Bevacizumab monoclonal antibodies using mass spectrometry. An isotopically labeled version is available as SILu^™Mab Bevacizumab (MSQC21).

SigmaMAb Bevacizumab is for R&D use only. Not for drug, household, or other uses.

애플리케이션

SILu^™ Lite SigmaMAb Bevacizumab Monoclonal Antibody has been used as a proangiogenic factor to study its role in the angiogenesis process by Raman spectroscopy.

생화학적/생리학적 작용

Bevacizumab serves as an antitumor agent. Studies show that chemotherapy using bevacizumab improves the condition of metastatic colorectal cancer and renal cell cancer patients.

서열

SigmaMab Bevacizumab Heavy Chain:
EVQLVESGGGLVQPGGSLRLSCAASGYTFTNYGMNWVRQAPGKGLEWVGWINTYTGEPTYAADFKRRFTFSLDTSKSTAYLQMNSLRAEDTAVYYCAKYPHYYGSSHWYFDVWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPG

SigmaMab Bevacizumab Light Chain:
DIQMTQSPSSLSASVGDRVTITCSASQDISNYLNWYQQKPGKAPKVLIYFTSSLHSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQYSTVPWTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC

법적 정보

SILu is a trademark of Sigma-Aldrich Co. LLC

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3