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Merck
모든 사진(3)

주요 문서

MAK069

Sigma-Aldrich

MPO Fluorometric Activity Assay Kit

sufficient for 100 fluorometric tests

동의어(들):

Myeoloperoxidase Fluorometric Activity Assay Kit

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About This Item

UNSPSC 코드:
12161503

사용

sufficient for 100 fluorometric tests

검출 방법

fluorometric

관련 질환(들)

cancer; cardiovascular diseases; hematological disorder

저장 온도

−20°C

유전자 정보

human ... MPO(4353)
mouse ... MPO(17523)
rat ... MPO(303413)

일반 설명

Myeloperoxidase (MPO) is a heme-containing enzyme that catalyzes the hydrogen peroxidase-mediated oxidation of halide ions to hypohalous acid. MPO is a lysosomal protein, highly expressed in neutrophils, that plays a role in the antimicrobial actions that occur as a result of neutrophil stimulation. The actions of MPO may also contribute to the initiation and pathogenesis of cardiovascular disease.

애플리케이션

MPO Fluorometric Activity Assay Kit has been used to determine the activity of myeloperoxidase.

적합성

Suitable for the measurement of myeloperoxidase (MPO) in biological samples such as tissue, cells, serum and white blood cells

원리

The MPO Activity Flurometric Assay kit provides a simple and direct procedure for measuring MPO activity in a variety of samples. In this assay, MPO catalyzes the formation of hypochlorous acid with reacts with the substrate, aminophenyl fluorescein, to generate fluorescein) (λex = 485/λem = 525 nm). One unit of MPO is the amount of enzyme that will oxidize the MPO substrate to yield 1.0 μmole of fluorescein per minute at room temperature.

교체됨

픽토그램

Health hazard

신호어

Danger

유해 및 위험 성명서

예방조치 성명서

Hazard Classifications

Resp. Sens. 1

Storage Class Code

10 - Combustible liquids


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