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Merck
모든 사진(4)

Key Documents

MAK043

Sigma-Aldrich

Cholesterol Quantitation Kit

sufficient for 100 colorimetric or fluorometric tests

동의어(들):

Cholesterol Assay Kit

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About This Item

UNSPSC 코드:
12161503
NACRES:
NA.25

사용

sufficient for 100 colorimetric or fluorometric tests

검출 방법

colorimetric
fluorometric

관련 질환(들)

cancer; cardiovascular diseases

저장 온도

−20°C

일반 설명

Cholesterol is an important component of mammalian cell membranes where it functions in intracellular transport, cell signaling, and maintaining membrane fluidity. Within the blood, cholesterol circulates as both the free acid and as cholesterol esters. Controlling serum cholesterol has an important therapeutic role as elevated cholesterol levels are associated with the development of atherosclerosis and cardiovascular pathologies. Recent evidence suggests a disturbance of cholesterol homeostasis contributes to the development of a chronic inflammatory state.

Cholesterol is predominantly produced in the liver. Abnormal cholesterol levels are implicated in coronary heart disease. Cholesterol is associated with breast cancer progression or inhibition. Tumor cells are capable of synthesizing their own cholesterol, which aids in cell proliferation. Increased cholesterol level is observed in cancers, especially in prostate cancer. Elevated serum cholesterol is observed in obesity.

애플리케이션

Cholesterol Quantitation Kit has been used to measure the total serum cholesterol level.

적합성

Suitable for use with cell and tissue culture samples, urine, plasma, serum, and other biological samples.

원리

The Cholesterol Quantitation Kit can also be used to determine the concentration of free cholesterol, cholesteryl esters, or both (total) present in a sample. In this kit, total cholesterol concentration is determined by a coupled enzyme assay, which results in a colorimetric (570 nm)/fluorometric (λex = 535/λem = 587 nm) product, proportional to the cholesterol present.

픽토그램

Health hazard

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class Code

10 - Combustible liquids

Flash Point (°F)

188.6 °F - closed cup

Flash Point (°C)

87 °C - closed cup


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

The role of cholesterol in cancer.
Kuzu O F, et al.
Cancer Research (2016)
Alessandro Attanzio et al.
Journal of the science of food and agriculture, 99(9), 4242-4247 (2019-02-26)
The stems of Opuntia ficus-indica, known as cladodes, are a rich source of soluble fibers, which makes them an important candidate for the production of functional foods. Tagliatelle of durum wheat fortified with Opuntia cladode extract (OCE) at different levels
Is There Any Relationship between Diabetic Gastroparesis and Mucosal Injury?
Cakir O O.
J Gastrointest Dig Syst , 6(461), 2-2 (2016)
Hypolipidemic and Anti-Atherogenic Activity of Aqueous Extract of Leaves of Lagenaria siceraria in Wistar Rats.
Aslam M and Nijam R
Journal of Natural Remedies, 14(1), 52-57 (2013)
Time trends in population cholesterol levels 1986--2004: influence of lipid-lowering drugs, obesity, smoking and educational level. The northern Sweden MONICA study
Eliasson M, et al.
J. Int. Med., 260(6), 551-559 (2006)

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