추천 제품
생물학적 소스
bovine submaxillary glands
Quality Level
유형
Type I-S
양식
powder
구성
Bound sialic acids, 9-24%
기술
electrophoresis: suitable
UniProt 수납 번호
저장 온도
−20°C
유전자 정보
cow ... BSM(286841)
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일반 설명
Mucin from bovine submaxillary glands is encoded by two bovine submaxillary BSM genes. It is present in the saliva and interacts with air and food. Mucin comprises three major domains namely N- and C terminal and the glycosylated proline, threonine and serine (PTS domain) central domain. The sialic acid contributes to 30% of the molecular weight of mucin. The central domain has many tandem repeats.
애플리케이션
Mucin from bovine submaxillary glands has been used:
- in the quantification of mucin
- as a component of artificial tear solution
- as a substrate for recombinant sialidase Gardnerella vaginalis
- to investigate a galactose-specific lectin from the red marine alga Ptilota filicina
- to study the characterization of a unique mucin-like glycoprotein secreted by a human endometrial adenocarcinoma cell line (Ishikawa)
생화학적/생리학적 작용
Albuminoid substance in mucus which gives it its ropy consistency
Bovine submaxillary mucin (BSM) is thermally stable up to 85°C. The terminal domain regions are key for the adsorption functionality of mucin.
결합
Similar to M 4503, but produced by Sigma.
기질
Neuraminidase substrate.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
이미 열람한 고객
Identification and characterization of NanH2 and NanH3, enzymes responsible for sialidase activity in the vaginal bacterium Gardnerella vaginalis
Robinson LS, et al.
Test, 294(14), 5230-5245 (2019)
Late therapeutic intervention with a respiratory syncytial virus L-protein polymerase inhibitor, PC786, on respiratory syncytial virus infection in human airway epithelium
Brookes DM, et al.
British Journal of Pharmacology, 175(12), 2520-2534 (2018)
Sasi B Yarragudi et al.
Carbohydrate polymers, 163, 216-226 (2017-03-08)
Targeted delivery and retention of drug formulations in the olfactory mucosa, the target site for nose-to-brain drug absorption is a major challenge due to the geometrical complexity of the nose and nasal clearance. Recent modelling data indicates that 10μm-sized microparticles
S Goswami et al.
Experimental lung research, 20(1), 85-100 (1994-01-01)
A human endometrial adenocarcinoma cell line (Ishikawa) has been shown to incorporate [3H]glucosamine and to secrete a radiolabeled high molecular weight compound which is excluded from a Sepharose CL-2B column. The excluded material was resistant to hyaluronidase, chondroitinase ABC, and
Instability and breakup of model tear films
Bhamla MS, et al.
Investigative Ophthalmology & Visual Science, 57(3), 949-958 (2016)
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