추천 제품
생물학적 소스
Canavalia ensiformis
유형
Type VI
형태
lyophilized powder
효능
≤20 μg per mL agglutination activity
불순물
Carbohydrate, essentially free
salt, essentially free
solubility
water: 1 % (w/v)
저장 온도
−20°C
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애플리케이션
Concanavalin A from Canavalia ensiformis (Jack bean) has been used for developing zwitterion-immobilized molecularly imprinted polymers (ziMIPs) for protein crystallization. It has been also used in the preparation of protein loaded microgels to prevent enzymatic degradation of microgels for monitoring by confocal laser scanning microscope (CLSM).
생화학적/생리학적 작용
Con A is not blood group specific but has an affinity for terminal α-D-mannosyl and α-D-glucosyl residues. Ca2+ and Mn2+ ions are required for activity. Con A dissociates into dimers at pH 5.6 or below. Between pH 5.8 and pH 7.0, Con A exists as a tetramer; above pH 7.0 higher aggregates are formed. Con A exhibits mitogenic activity which is dependent on its degree of aggregation. Succinylation results in an active dimeric form which remains a dimer above pH 5.6.
제조 메모
Highly purified by specific affinity chromatography.
분석 메모
Agglutination activity: Determined from serial dilutions of a 1 mg/mL solution (this activity is the lowest conc. to agglutinate a 2% suspension of human erythrocytes after 1 hr incubation at 25 °C). Requires Type A Human Blood.
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Repr. 2 - Resp. Sens. 1 - Skin Sens. 1
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Zwitterion-Immobilized Imprinted Polymers for Promoting the Crystallization of Proteins
Xing Y, et al.
Crystal Growth & Design, 15(10), 4932-4937 (2015)
Derivatization of epoxy-activated agarose with various carbohydrates for the preparation of stable and high-capacity affinity adsorbents: their use for affinity chromatography of carbohydrate-binding proteins.
I Matsumoto et al.
Analytical biochemistry, 116(1), 103-110 (1981-09-01)
Zuobing Zhang et al.
Biology, 9(5) (2020-05-30)
The Chinese soft-shelled turtle (Pelodiscus sinesis) is a widely cultured commercial species in East and Southeast Asian countries. The turtles frequently suffer from acute cold stress during farming in China. Stress-induced factor such as Interleukin-6 (IL6) is a multifunctional molecule
Chain and pore-blocking effects on matrix degradation in protein-loaded microgels
Widenbring R, et al.
Biomacromolecules, 15(10), 3671-3678 (2014)
Lindsay Kosack et al.
Scientific reports, 7(1), 11289-11289 (2017-09-14)
Lipid metabolism is increasingly being appreciated to affect immunoregulation, inflammation and pathology. In this study we found that mice infected with lymphocytic choriomeningitis virus (LCMV) exhibit global perturbations of circulating serum lipids. Mice lacking the lipid-sensing surface receptor triggering receptor
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