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일반 설명
Peanut lectin (PNA) is a lectin or an agglutinin from the legume, Arachis hypogaea, found in peripheral venous blood in humans after ingestion of peanuts. PNA lectin is specific to the galactosyl (β-1,3) N-acetylgalactosamine.
애플리케이션
Lectin from Arachis hypogaea (peanut) has been used:
- in enzyme-linked micro plate assay to detect β-D-galactose-N-acetylglucosamine
- in Immunohistochemical double staining
- Immunohistochemical double staining for the detection of germinal centers
- in enzyme-linked microplate assayto detect β-D-galactose-N-acetylglucosamine
생화학적/생리학적 작용
Lectin from Arachis hypogaea (peanut) functions as an antigenic determinant for Thomsen-Friedenreich antigen (TF) and as mitogen for colorectal cancer stimulation cell division in normal colonic epithelium. It is therefore used as tumor marker.
PNA does not agglutinate normal human erythrocytes, but strongly agglutinates neuraminidase treated erythrocytes. PNA has potent anti-T activity similar to the anti-T antibody in human sera. The lectin can be used to distinguish between human lymphocyte subsets.
포장
Package size based on protein content.
물리적 형태
Contains sodium citrate
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
이미 열람한 고객
Synthesis of glycopolymers and their multivalent recognitions with lectins
Polym. Chem., 1, 1392-1412 (2010)
Inhibition of influenza viral neuraminidase activity by collectins
Archives of Virology, 1731-1742 (2007)
Diagnostic value of lectins in differentiation of molar placentas
Iranian Journal of Basic Medical Sciences, 15, 1140-1140 (2012)
Peanut (Arachis hypogaea) lectin recognizes α−linked galactose, but not N-acetyl lactosamine in N-linked oligosaccharide terminals
International Journal of Biological Macromolecules, 28, 365-371 (2001)
In situ observation of germinal center cell apoptosis during a secondary immune response
Journal of Clinical and Experimental Hematopathology : JCEH, 46, 73-82 (2006)
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