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Merck
모든 사진(1)

주요 문서

L6135

Sigma-Aldrich

Lectin from Arachis hypogaea (peanut)

biotin conjugate, lyophilized powder

동의어(들):

PNA, Peanut agglutinin

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About This Item

UNSPSC 코드:
12352202
NACRES:
NA.32

결합

biotin conjugate

Quality Level

양식

lyophilized powder

분자량

120 kDa

구성

Protein, ≥80% Lowry

라벨링 범위

~3 mol biotin per mol protein

기술

blood typing: suitable
fractionation: suitable

solubility

water: 1.00-1.10 mg/mL, clear to slightly hazy, colorless

저장 온도

2-8°C

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일반 설명

Peanut lectin (PNA) is a lectin or an agglutinin from the legume, Arachis hypogaea, found in peripheral venous blood in humans after ingestion of peanuts. PNA lectin is specific to the galactosyl (β-1,3) N-acetylgalactosamine.

애플리케이션

Lectin from Arachis hypogaea (peanut) has been used:
  • in enzyme-linked micro plate assay to detect β-D-galactose-N-acetylglucosamine
  • in Immunohistochemical double staining
  • Immunohistochemical double staining for the detection of germinal centers
  • in enzyme-linked microplate assayto detect β-D-galactose-N-acetylglucosamine

생화학적/생리학적 작용

Lectin from Arachis hypogaea (peanut) functions as an antigenic determinant for Thomsen-Friedenreich antigen (TF) and as mitogen for colorectal cancer stimulation cell division in normal colonic epithelium. It is therefore used as tumor marker.
PNA does not agglutinate normal human erythrocytes, but strongly agglutinates neuraminidase treated erythrocytes. PNA has potent anti-T activity similar to the anti-T antibody in human sera. The lectin can be used to distinguish between human lymphocyte subsets.

포장

Package size based on protein content.

물리적 형태

Contains sodium citrate

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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문서 라이브러리 방문

Synthesis of glycopolymers and their multivalent recognitions with lectins
Ting SRS, et al.
Polym. Chem., 1, 1392-1412 (2010)
Inhibition of influenza viral neuraminidase activity by collectins
Tecle T, et al.
Archives of Virology, 1731-1742 (2007)
Diagnostic value of lectins in differentiation of molar placentas
Pasdar FA, et al.
Iranian Journal of Basic Medical Sciences, 15, 1140-1140 (2012)
Peanut (Arachis hypogaea) lectin recognizes α−linked galactose, but not N-acetyl lactosamine in N-linked oligosaccharide terminals
Chacko BK and Appukuttan PS
International Journal of Biological Macromolecules, 28, 365-371 (2001)
In situ observation of germinal center cell apoptosis during a secondary immune response
Saitoh HA, et al.
Journal of Clinical and Experimental Hematopathology : JCEH, 46, 73-82 (2006)

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