H9415
5HPP-33
≥98% (HPLC), solid
동의어(들):
2-[2,6-bis(1-Methylethyl)phenyl]-5-hydroxy-1H-isoindole-1,3(2H)-dione, 5-Hydroxy-2-(2,6-diisopropylphenyl)-1H-isoindole-1,3-dione
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모든 사진(1)
About This Item
실험식(Hill 표기법):
C20H21NO3
CAS Number:
Molecular Weight:
323.39
MDL number:
UNSPSC 코드:
12352200
PubChem Substance ID:
NACRES:
NA.77
추천 제품
분석
≥98% (HPLC)
양식
solid
색상
white to off-white
solubility
DMSO: >20 mg/mL
저장 온도
2-8°C
SMILES string
CC(C)c1cccc(C(C)C)c1N2C(=O)c3ccc(O)cc3C2=O
InChI
1S/C20H21NO3/c1-11(2)14-6-5-7-15(12(3)4)18(14)21-19(23)16-9-8-13(22)10-17(16)20(21)24/h5-12,22H,1-4H3
InChI key
LAKWINYVWJPHQW-UHFFFAOYSA-N
생화학적/생리학적 작용
5HPP-33 is a thalidomide derivative which was reported to be active as anticancer agent through stabilization of the microtubules.
5HPP-33 is a thalidomide derivative which was reported to be active as anticancer agent through stabilization of the microtubules. 5HPP-33 has shown inhibition of cell proliferation of both estrogen-dependent (MCF-7) and estrogen-independent (MDA-MB-231) breast cancer cells as well as other cell lines. A study in tubulin forming assay reported that 5HPP-33 acts as a microtubule formation inhibitor (IC50=810 nM).
신호어
Warning
유해 및 위험 성명서
예방조치 성명서
Hazard Classifications
Aquatic Acute 1 - Aquatic Chronic 1
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
dust mask type N95 (US), Eyeshields, Gloves
가장 최신 버전 중 하나를 선택하세요:
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Maria Ivshina et al.
Molecular and cellular biology, 35(3), 610-618 (2014-12-03)
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