H5916

Human Growth Hormone

HumanKine^®, recombinant, Xeno-free, >95% (SDS-PAGE), suitable for cell culture

• 동의어(들): HGH
• UNSPSC 코드: 12352202
• NACRES: NA.77

속성

• product name: Human Growth Hormone human, HGH, recombinant, expressed in HEK 293 cells, HumanKine^®, suitable for cell culture
• 생물학적 소스: human
• Quality Level: 100
• 재조합: expressed in HEK 293 cells
• 분석: ≥95% (SDS-PAGE)
• 형태: lyophilized powder
• 효능: ≤0.5 ng/mL EC₅₀
• 분자량: monomer 22 kDa (non-glycosylated)
• 포장: pkg of 10 μg
• 저장 조건: avoid repeated freeze/thaw cycles
• 기술: cell culture | mammalian: suitable
• 불순물: ≤1 EU/mg
• 저장 온도: −20°C

설명

일반 설명

Human growth hormone (HGH), also called somatotropin, is a peptide hormone that consists of a long single chain of amino acids. It is naturally secreted by somatotropic cells in the anterior pituitary gland of the human body.

애플리케이션

Human Growth Hormone human has been used as a supplement in culture media to study its effect on the immune response in fish cell lines. It has also been used as a supplement in biliary differentiation medium (BDM) for differentiation of human embryonic stem cells (hESCs)/ human induced pluripotent stem cells (hiPSCs)-derived hepatoblasts.

생화학적/생리학적 작용

Human growth hormone (HGH) is required for normal human growth and development. HGH modifies a variety of physiological functions by stimulating the expression of insulin-like growth factor I and increases calcium retention and bone density. HGH increases muscle mass, promotes lipolysis, and reduces liver uptake of glucose. Abnormalities in the regulation of HGH lead to various growth disorders such as gigantism or acromegaly due to hypersecretion of HGH. Conversely, HGH deficiency leads to growth deficit in children and GH deficiency syndrome in adults.

물리적 형태

Lyophilized from a 0.2 μm filtered solution of 1x PBS.

제조 메모

HumanKine, Human Growth Hormone (HGH) is expressed as a non-glycosylated monomer in human HEK 293 cells and has an apparent molecular mass of 22 kDa.

분석 메모

The activity was determined by the dose-dependent stimulation of the proliferation of rat lymphoma line Nb2-11 cells (prolactin indicator cell line).

법적 정보

HumanKine is a registered trademark of Proteintech Group, Inc. and Humanzyme, Inc

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable