H4628

DL-Homocysteine

≥95% (titration)

• 동의어(들): 2-Amino-4-mercaptobutyric acid
• Linear Formula: HSCH₂CH₂CH(NH₂)COOH
• CAS Number: 454-29-5
• Molecular Weight: 135.18
• Beilstein: 1721683
• EC Number: 207-222-9
• MDL number: MFCD00004898
• UNSPSC 코드: 12352209
• eCl@ss: 42021308
• PubChem Substance ID: 24895646
• NACRES: NA.26

속성

• product name: DL-Homocysteine, ≥95% (titration)
• Quality Level: 200
• 분석: ≥95% (titration)
• 형태: powder
• mp: 232-233 °C (lit.)
• solubility: H₂O: soluble
• 응용 분야: cell analysis; peptide synthesis
• 저장 온도: −20°C
• SMILES string: NC(CCS)C(O)=O
• InChI: 1S/C4H9NO2S/c5-3(1-2-8)4(6)7/h3,8H,1-2,5H2,(H,6,7)
• InChI key: FFFHZYDWPBMWHY-UHFFFAOYSA-N

설명

애플리케이션

DL-Homocysteine has been used to induce hyperhomocysteinemia in Sprague–Dawley rats. It has also been used to study the effects of hyperhomocysteinemia on atherosclerosis in apolipoprotein E-deficient mice.

생화학적/생리학적 작용

Homocysteine is a sulfhydryl-containing amino acid, synthesized from methionine. It is a non-essential, non-proteinogenic amino acid. It is an important determinant of the methylation cycle and is present in the plasma in four forms. An abnormally high level of homocysteine leads to hyperhomocysteinemia and also promotes atherosclerosis.

Increased plasma homocysteine is a risk factor for coronary heart disease and carcinogenesis; may be a marker for tumor cell growth.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)