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Merck
모든 사진(1)

주요 문서

H3261

Sigma-Aldrich

2-Mercaptopyridine N-oxide sodium salt

≥96%

동의어(들):

Sodium Omadine, Sodium pyrithione, 1-Hydroxy-2-pyridinethione sodium salt, 2-Mercaptopyridine-1-oxide sodium salt, 2-Pyridinethiol-1-oxide sodium salt, Pyrithione sodium salt

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About This Item

실험식(Hill 표기법):
C5H4NNaOS
CAS Number:
Molecular Weight:
149.15
Beilstein:
4026050
EC Number:
MDL number:
UNSPSC 코드:
51102829
PubChem Substance ID:
NACRES:
NA.85

생물학적 소스

synthetic

Quality Level

분석

≥96%

색상

faintly beige
white to light yellow

solubility

H2O: 50 mg/mL

항생제 활성 스펙트럼

fungi

동작 모드

cell membrane | interferes

SMILES string

[Na+].[O-][n+]1ccccc1[S-]

InChI

1S/C5H5NOS.Na/c7-6-4-2-1-3-5(6)8;/h1-4,8H;/q;+1/p-1

InChI key

WNGMMIYXPIAYOB-UHFFFAOYSA-M

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애플리케이션

2-Mercaptopyridine N-oxide can be used to generate bidentate oxothiolane chelates with transition metals.
2-Mercaptopyridine N-oxide, also called pyrithione, is added to cells in culture so metals enter them readily without relying on transporters. It is used to study picornavirus infections.

생화학적/생리학적 작용

2-Mercaptopyridine N-oxide is a zinc ionophore that transports zinc into cells.

픽토그램

Skull and crossbonesHealth hazardEnvironment

신호어

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 1

표적 기관

Nervous system

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves


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문서 라이브러리 방문

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Antonia A Nemec et al.
American journal of respiratory cell and molecular biology, 41(1), 69-75 (2008-12-23)
We recently reported that induction of metallothionein (MT) was critical in limiting nickel (Ni)-induced lung injury in intact mice. Nonetheless, the mechanism by which Ni induces MT expression is unclear. We hypothesized that the ability of Ni to mobilize zinc
B M Krenn et al.
Journal of virology, 83(1), 58-64 (2008-10-17)
We have discovered two metal ion binding compounds, pyrithione (PT) and hinokitiol (HK), that efficiently inhibit human rhinovirus, coxsackievirus, and mengovirus multiplication. Early stages of virus infection are unaffected by these compounds. However, the cleavage of the cellular eukaryotic translation
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