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G8168

Sigma-Aldrich

G418 disulfate salt

solution, non-animal origin, suitable for cell culture, BioReagent

동의어(들):

Antibiotic G418

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About This Item

실험식(Hill 표기법):
C20H40N4O10 · 2H2SO4
CAS Number:
108321-42-2
Molecular Weight:
692.71
MDL number:
MFCD00058314
UNSPSC 코드:
12352207
PubChem Substance ID:
24895333
NACRES:
NA.76

product name

G 418 disulfate salt solution, 50 mg/mL in H2O, 0.1 μm filtered, BioReagent, suitable for cell culture

생물학적 소스

Micromonospora echinospora

Quality Level

200

무균

0.1 μm filtered

제품 라인

BioReagent

형태

solution

효능

50-60 mg per mL

분자량

692.7

포장

pkg of 10 and 100 mL

농도

50 mg/mL in H2O

기술

cell culture | mammalian: suitable

불순물

endotoxin, tested

색상

colorless

solubility

H2O: 50 mg/mL, clear

항생제 활성 스펙트럼

parasites

동작 모드

protein synthesis | interferes

저장 온도

2-8°C

SMILES string

OS(O)(=O)=O.OS(O)(=O)=O.CN[C@H]1[C@H](O)[C@@H](OC[C@@]1(C)O)O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@H]3O[C@H]([C@H](C)O)[C@@H](O)[C@H](O)[C@H]3N)[C@@H]2O

InChI

1S/C20H40N4O10.2H2O4S/c1-6(25)14-11(27)10(26)9(23)18(32-14)33-15-7(21)4-8(22)16(12(15)28)34-19-13(29)17(24-3)20(2,30)5-31-19;2*1-5(2,3)4/h6-19,24-30H,4-5,21-23H2,1-3H3;2*(H2,1,2,3,4)/t6?,7-,8+,9+,10+,11-,12-,13-,14+,15+,16-,17-,18+,19-,20+;;/m0../s1

InChI key

UHEPSJJJMTWUCP-NKCAIAFTSA-N

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일반 설명

Chemical structure: aminoglycoside

애플리케이션

G418 disulfate is an aminoglycoside antibiotic similar in structure to gentamicin used for selection and maintenance of prokaryotic and eukaryotic cells. Optimal concentrations for selection and maintenance vary by cell lines. Bacteria and algae require 5 μg/mL or less while animal cells may require 300-500 μg/mL.

생화학적/생리학적 작용

Mode of Action: G418 blocks polypeptide synthesis and protein elongation by inhibiting synthesis at the 70S and 80S ribosomes.

Antimicrobial Spectrum: G418 selects for cells stably transfected with an iNOS promoter construct and neomycin resistance gene and shows activity against protozoa and helminthes.

주의사항

The product is stable for two years when stored at 2-8°C.

픽토그램

Health hazard
GHS08

신호어

Danger

유해 및 위험 성명서

H317,H334

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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