G7384

Gallic acid

97.5-102.5% (titration)

• 동의어(들): 3,4,5-Trihydroxybenzoic acid
• Linear Formula: (HO)₃C₆H₂CO₂H
• CAS Number: 149-91-7
• Molecular Weight: 170.12
• Beilstein: 2050274
• EC Number: 205-749-9
• MDL number: MFCD00002510
• UNSPSC 코드: 12352205
• PubChem Substance ID: 24895304
• NACRES: NA.25

속성

• 생물학적 소스: plant fruit
• Quality Level: 200
• 분석: 97.5-102.5% (titration)
• 형태: powder
• 기술: HPLC: suitable
• 색상: white to beige
• mp: 251 °C (dec.) (lit.)
• solubility: ethanol: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow
• 적합성: suitable for UV spectrophotometry and general use; suitable for absorption spectrum analysis
• 응용 분야: agriculture; metabolomics; microbiology; vitamins, nutraceuticals, and natural products; vitamins, nutraceuticals, and natural products
• SMILES string: OC(=O)c1cc(O)c(O)c(O)c1
• InChI: 1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12)
• InChI key: LNTHITQWFMADLM-UHFFFAOYSA-N

설명

일반 설명

Gallic acid, also known as 3,4,5-Trihydroxybenzoic acid, is a natural polyhydroxyphenolic compound commonly found in many fruits and plants, including grapes, tea, and oak bark, either in the free acid form or esterified as gallotannins and ellagitannins. Existing research suggests that this plant-derived metabolite is an astringent, a cyclooxygenase-2 (COX-2) and histone acetyltransferase inhibitor, and an apoptosis inducer with various biological activities. These activities include antioxidant, antifungal, gastroprotective, neuroprotective, cardioprotective, antimicrobial, anti-inflammatory, anti-tumor, anti-tyrosinase, and anticancer effects.

애플리케이션

Gallic acid has been used:

• as a standard for the quantification of extractable phenolics by external calibration
• as a standard to determine the total tannin content of oak root powder using the Folin-Ciocalteu method
• as a phenolic acid to study it′s in vitro antiviral, antibacterial, cytotoxicity and antifungal activities

Gallic acid is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical and biochemical research.

생화학적/생리학적 작용

Gallic acid is a water soluble phenolic acid present in grapes and in the leaves of many plants. Gallic acid esters, such as tannins, catechin gallates and aliphatic gallates are potent antioxidants in vitro. However, gallic acid itself also appears to have antioxidant, anticarcinogenic and antiangiogenic activity in vitro.

특징 및 장점

• High quality compound suitable for multiple research applications
• Compatible with HPLC and mass spectrometry techniques

기타 정보

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안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315,H319,H335
• 예방조치 성명서: P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves