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Merck
모든 사진(1)

Key Documents

D3822

Sigma-Aldrich

Dipeptidyl Peptidase IV Inhibitor I

동의어(들):

Diprotin A

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About This Item

실험식(Hill 표기법):
C17H31N3O4
Molecular Weight:
341.45
UNSPSC 코드:
12352202
NACRES:
NA.77

분석

≥95% (HPLC)

Quality Level

형태

solid

색상

white

저장 온도

2-8°C

일반 설명

Dipeptidyl peptidase IV (DPP IV) is a member of the prolyl-specific proteases family. It is a dimeric type II integral membrane glycoprotein that is broadly expressed in the epithelial and nonepithelial tissues. It is majorly expressed in the kidney and the colon. 

애플리케이션

Dipeptidyl peptidase IV inhibitor I has been used in acute in vivo studies to assess rapid plasma glucagon-like peptide (GLP-1) responses to specified secretory agents in mice.

생화학적/생리학적 작용

Dipeptidyl peptidase IV (DPP IV) functions as a modulator of glucagon-like peptide (GLP-1), insulin-stimulating hormones, and glucose-dependent insulinotropic polypeptide (GIP). It is an essential therapeutic target for type 2 diabetes (T2DM). DPP-4 inhibitors are crucial for maintaining glucose homeostasis by prolonging the activity of GLP-1 and GIP. They also enhance glycemic control for a longer period when compared to early oral hypoglycemics. DPP-4 also acts as a binding protein and a ligand of extracellular factors.

서열

Ile-Pro-Ile

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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