추천 제품
product name
Aprotinin from bovine lung, saline solution, 3-7 TIU/mg protein
생물학적 소스
bovine
Quality Level
무균
aseptically filled
형태
saline solution
특이 활성도
3-7 TIU/mg protein
분자량
~6,500
solubility
H2O: soluble >10 mg/mL
UniProt 수납 번호
저장 온도
2-8°C
InChI key
ZPNFWUPYTFPOJU-UHFFFAOYSA-N
유전자 정보
cow ... PTI(404172)
유사한 제품을 찾으십니까? 방문 제품 비교 안내
일반 설명
Aprotinin is a 58 amino acid-long protein, with a calculated molecular weight of 6512 Da, that acts as a serine protease inhibitor. Known also as bovine pancreatic trypsin inhibitor (BPTI), aprotinin inhibits serine proteases such as chymotrypsin, kallikrein, plasmin and trypsin.
애플리케이션
Aprotinin is largely used as an inhibitor of trypsin.
생화학적/생리학적 작용
Aprotinin is a competitive serine protease inhibitor that forms stable complexes with and blocks the active sites of enzyme. This binding is reversible, and most aprotinin-protease complexes will dissociate at extreme pH levels >10 or <3. Structurally, Aprotinin is a monomeric globular protein derived from bovine lung that consists of 58 amino acids, arranged in a single polypeptide chain with three crosslinking disulfide bridges.
주의사항
Aprotinin products should be stored at 2-8°C.
단위 정의
One Trypsin Inhibitor Unit (TIU) will decrease the activity of two trypsin units by 50%, where one trypsin unit will hydrolyze 1.0 μmole of N-alpha-benzoyl-DL-arginine p-nitroanilide per minute at pH 7.8 and 25°C. Another commonly used unit is the KIU, with 1 TIU = 1,300 KIU.
제조 메모
This product is an aseptically filled solution in 0.9% NaCl and 0.9% benzyl alcohol. It has an activity of 3-7 TIU/mg protein and 3-21 TIU/mL solution.
Storage Class Code
12 - Non Combustible Liquids
WGK
nwg
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
이미 열람한 고객
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Tyrosine kinases drive the proliferation and survival of many human cancers. Thus profiling the global state of tyrosine phosphorylation of a tumor is likely to provide a wealth of information that can be used to classify tumors for prognosis and
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American journal of obstetrics and gynecology, 189(2), 613-613 (2003-10-04)
William M Maniscalco et al.
American journal of physiology. Lung cellular and molecular physiology, 282(4), L811-L823 (2002-03-07)
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E M Benkhart et al.
Journal of immunology (Baltimore, Md. : 1950), 165(3), 1612-1617 (2000-07-21)
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프로토콜
Enzymatic Assay of Aprotinin
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