콘텐츠로 건너뛰기
Merck
모든 사진(1)

문서

D1822

Sigma-Aldrich

Doxycycline monohydrate

동의어(들):

6-Deoxy-5-oxytetracycline monohydrate, Doxycycline

로그인조직 및 계약 가격 보기
모든 사진(1)

About This Item

실험식(Hill 표기법):
C22H24N2O8 · H2O
CAS Number:
17086-28-1
Molecular Weight:
462.45
MDL number:
MFCD02682958
UNSPSC 코드:
51101500
PubChem Substance ID:
329798712
NACRES:
NA.85

형태

powder or crystals

Quality Level

200

항생제 활성 스펙트럼

Gram-negative bacteria
Gram-positive bacteria
mycoplasma
parasites

동작 모드

protein synthesis | interferes

저장 온도

−20°C

SMILES string

O.C[C@@H]1[C@H]2[C@H](O)[C@H]3[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]3(O)C(O)=C2C(=O)c4c(O)cccc14

InChI

1S/C22H24N2O8.H2O/c1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29;/h4-7,10,14-15,17,25,27-29,32H,1-3H3,(H2,23,31);1H2/t7-,10+,14+,15-,17-,22-;/m0./s1

InChI key

XQTWDDCIUJNLTR-CVHRZJFOSA-N

유전자 정보

human ... MMP1(4312) , MMP13(4322) , MMP7(4316) , MMP8(4317)

유사한 제품을 찾으십니까? 방문 제품 비교 안내

관련 카테고리

애플리케이션

  • In yeast cells, doxycycline has been used in doxycycline-inducible system for overexpression of methyltransferase Hmt1 (hnRNP methyltransferase 1).
  • It has been used in the doxycycline-inducible IFITM (interferon-induced transmembrane) cell lines.
  • It has also been used as an antimicrobial agent.

생화학적/생리학적 작용

Doxycycline is a semisynthetic tetracycline that is active against bacteria, mycoplasma and protozoan parasites. It inhibits the bacterial protein synthesis by inhibiting the interaction of aminoacyl-tRNA and the bacterial ribosome.

기타 정보

Keep container tightly closed in a dry and well-ventilated place.

픽토그램

Exclamation mark
GHS07

신호어

Warning

유해 및 위험 성명서

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

I Chopra et al.
Microbiology and molecular biology reviews : MMBR, 65(2), 232-60 (2001-05-31)
Tetracyclines were discovered in the 1940s and exhibited activity against a wide range of microorganisms including gram-positive and gram-negative bacteria, chlamydiae, mycoplasmas, rickettsiae, and protozoan parasites. They are inexpensive antibiotics, which have been used extensively in the prophlylaxis and therapy
Yeast Hmt1 catalyses asymmetric dimethylation of histone H3 arginine 2 in vitro.
Li HT, et al.
The Biochemical Journal, 467, 507-515 (2015)
In vitro antimicrobial susceptibility testing of bacterial enteropathogens causing traveler's diarrhea in four geographic regions.
Gomi H, et al.
Antimicrobial Agents and Chemotherapy, 45, 212-216 (2001)
Uninterpretable cerebrospinal fluid absorbance scan caused by doxycycline therapy.
Jan Miller
Annals of clinical biochemistry, 56(5), 619-622 (2019-06-07)
Andi Dian Permana et al.
Pharmaceutics, 11(7) (2019-07-20)
Conventional oral administration of antifilariasis drugs results in nonspecific targeting of the drugs and the intradermal delivery of nanoparticles with sizes of <100 nm could be used to improve lymphatic uptake. This study investigated the combination of nanosuspension and dissolving
모든 관련된 서류 보기

자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..

고객지원팀으로 연락바랍니다.