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Merck
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Key Documents

87128

Sigma-Aldrich

Tetracycline

98.0-102.0% (HPLC)

동의어(들):

Tetracycline HCL, Tetracycline Monohydrochloride

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About This Item

실험식(Hill 표기법):
C22H24N2O8 · xH2O
CAS Number:
Molecular Weight:
444.43 (anhydrous basis)
Beilstein:
2230417
EC Number:
MDL number:
UNSPSC 코드:
51284017
PubChem Substance ID:
NACRES:
NA.85

생물학적 소스

synthetic

Quality Level

분석

98.0-102.0% (HPLC)

형태

powder or crystals

색상

faint yellow to dark yellow

mp

172-174 °C (dec.)

항생제 활성 스펙트럼

Gram-negative bacteria
Gram-positive bacteria

동작 모드

protein synthesis | interferes

저장 온도

2-8°C

SMILES string

CN(C)[C@H]1[C@@H]2C[C@H]3C(=C(O)[C@]2(O)C(=O)C(C(N)=O)=C1O)C(=O)c4c(O)cccc4[C@@]3(C)O

InChI

1S/C22H24N2O8/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28/h4-6,9-10,15,25,27-28,31-32H,7H2,1-3H3,(H2,23,30)/t9-,10-,15-,21+,22-/m0/s1

InChI key

OFVLGDICTFRJMM-WESIUVDSSA-N

유전자 정보

유사한 제품을 찾으십니까? 방문 제품 비교 안내

일반 설명

Chemical structure: tetracycline

생화학적/생리학적 작용

Mode of Action: Tetracycline passively diffuses through proin channels in the cell membrane, binding to 30S ribosomes and inhibits protein synthesis by preventing access of aminoacyl tRNA to the acceptor site on the mRNA-ribosome complex. It also binds to the bacterial 50S ribosomal subunit, altering the membrane and causing intracellular components to leak from bacterial cells. The inhibitory effects can be reversed by washing, suggesting that it is the reversibly bound antibiotic, and not the irreversibly bound drug, that is responsible for antibacterial action.

Mode of Resistance: The effects are inactivated via a loss of cell wall permeability.

Antimicrobial spectrum: Includes a wide range of antimicrobial activity against gram-positive and gram-negative bacteria.

포장

25g, 100g

기타 정보

Keep container tightly closed in a dry and well-ventilated place.Hygroscopic. Light sensitive. Keep in a dry place.

관련 제품

제품 번호
설명
가격

픽토그램

Health hazardExclamation markEnvironment

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Repr. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves


시험 성적서(COA)

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