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Merck
모든 사진(2)

Key Documents

C0330

Sigma-Aldrich

Ciprofibrate

동의어(들):

2-[p-(2,2-Dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid

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About This Item

실험식(Hill 표기법):
C13H14Cl2O3
CAS Number:
Molecular Weight:
289.15
EC Number:
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:
NACRES:
NA.77

형태

powder

Quality Level

저장 온도

2-8°C

SMILES string

CC(C)(Oc1ccc(cc1)C2CC2(Cl)Cl)C(O)=O

InChI

1S/C13H14Cl2O3/c1-12(2,11(16)17)18-9-5-3-8(4-6-9)10-7-13(10,14)15/h3-6,10H,7H2,1-2H3,(H,16,17)

InChI key

KPSRODZRAIWAKH-UHFFFAOYSA-N

유전자 정보

human ... PPARA(5465)

유사한 제품을 찾으십니까? 방문 제품 비교 안내

생화학적/생리학적 작용

Peroxisome proliferator-activated receptor α (PPARα) agonist

픽토그램

Health hazard

신호어

Danger

유해 및 위험 성명서

예방조치 성명서

Hazard Classifications

Carc. 1B

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges


시험 성적서(COA)

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문서 라이브러리 방문

P Passilly et al.
Biochemical pharmacology, 58(6), 1001-1008 (1999-10-06)
The basic mechanism(s) by which peroxisome proliferators activate peroxisome proliferator-activated receptors (PPARs) is (are) not yet fully understood. Given the diversity of peroxisome proliferators, several hypotheses of activation have been proposed. Among them is the notion that peroxisome proliferators could
György Paragh et al.
British journal of clinical pharmacology, 61(6), 694-701 (2006-05-26)
Diabetic dyslipidaemia with decreased high-density lipoprotein-cholesterol (HDL-C) concentration plays a key role in enhanced atherosclerosis. The antioxidant effect of HDL is due to the influence of human paraoxonase 1 (PON1) and several authors have described decreased activity of this enzyme
V Goll et al.
Toxicology and applied pharmacology, 160(1), 21-32 (1999-09-30)
Peroxisome proliferators (PPs) are a class of rodent nongenotoxic hepatocarcinogens that cause hepatocyte peroxisome proliferation, increased DNA synthesis, and decreased spontaneous apoptosis. We examined the effects of various PPs such as the hypolipidemic agents clofibric acid (CLO), bezafibrate (BEZA), ciprofibrate
Alessandro Antonelli et al.
Experimental cell research, 317(11), 1527-1533 (2011-05-14)
Until now, no data are present about the effect of peroxisome proliferator-activated receptor (PPAR)α activation on the prototype Th1 [chemokine (C-X-C motif) ligand (CXCL)10] (CXCL10) and Th2 [chemokine (C-C motif) ligand 2] (CCL2) chemokines secretion in thyroid cells. The role
Zakaria El Kebbaj et al.
Endocrinology, 150(3), 1192-1201 (2008-10-25)
Seasonal obesity and fasting-associated hibernation are the two major metabolic events governing hepatic lipid metabolism in hibernating mammals. In this process, however, the role of the nuclear receptor known as peroxisome proliferator-activated receptor (PPAR)-alpha has not been elucidated yet. Here

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