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Merck
모든 사진(4)

주요 문서

A9883

Sigma-Aldrich

ADA

≥98% (titration)

동의어(들):

N-(2-Acetamido)iminodiacetic acid, N-(Carbamoylmethyl)iminodiacetic acid

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About This Item

Linear Formula:
H2NCOCH2N(CH2CO2H)2
CAS Number:
Molecular Weight:
190.15
Beilstein:
1787181
EC Number:
MDL number:
UNSPSC 코드:
12161700
PubChem Substance ID:
NACRES:
NA.25

Quality Level

분석

≥98% (titration)

양식

powder

pH

1.5-3.0

유용한 pH 범위

6.0-7.2

pKa(25 °C)

6.6

mp

219 °C (dec.) (lit.)

solubility

1 M NaOH: 160 mg/mL, clear, colorless

응용 분야

diagnostic assay manufacturing

저장 온도

room temp

SMILES string

NC(=O)CN(CC(O)=O)CC(O)=O

InChI

1S/C6H10N2O5/c7-4(9)1-8(2-5(10)11)3-6(12)13/h1-3H2,(H2,7,9)(H,10,11)(H,12,13)

InChI key

QZTKDVCDBIDYMD-UHFFFAOYSA-N

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일반 설명

ADA is a zwitterionic buffer used in biochemistry and molecular biology. It is one of the Good buffers developed in the 1960′s to provide buffers in the pH range of 6.15 - 8.35 for wide applicability to biochemical studies. The pioneering publication by Good and co-workers describes the synthesis of ADA and its physical properties. The useful range of ADA buffer in aqueous solution is 6.0 - 7.2.

애플리케이션

Biological buffer component with sodium hydroxide and sodium chloride (pH 5.67-7.57, useful pH range 6.4-7.4). Used to prepare immobilized pH gradients.

제조 메모

This product is soluble in 1 M NaOH (160mg/mL), yielding a clear, colorless solution.

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

예방조치 성명서

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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문서 라이브러리 방문

Hydrogen ion buffers for biological research
Good NE, et al.
Biochemistry, 5( (2), 467-477 (1966)
Gulen Yesilbag Tonga et al.
Nature chemistry, 7(7), 597-603 (2015-06-24)
Bioorthogonal catalysis broadens the functional possibilities of intracellular chemistry. Effective delivery and regulation of synthetic catalytic systems in cells are challenging due to the complex intracellular environment and catalyst instability. Here, we report the fabrication of protein-sized bioorthogonal nanozymes through
Eoin Gillespie et al.
Journal of separation science, 32(15-16), 2659-2667 (2009-07-09)
The application of scanning capacitively coupled contactless conductivity detection (SC(4)D) for the determination of pH dependant behaviour of two aminopolycarboxylates immobilised onto the surface of a monolithic capillary column is described. The use of SC(4)D to visualise changes in conductivity
E A Lance et al.
Analytical biochemistry, 133(2), 492-501 (1983-09-01)
Potentiometric, visible, infrared, electron spin, and nuclear magnetic resonance studies of the complexation of N-(2-acetamido)iminodiacetic acid (H2ADA) by Ca(II), Mg(II), Mn(II), Zn(II), Co(II), Ni(II), and Cu(II) are reported. Ca(II) and Mg(II) were found not to form 2:1 ADA2- to M(II)
Christopher J Smiley et al.
Journal of the American Dental Association (1939), 146(7), 508-524 (2015-06-27)
Conduct a systematic review and meta-analysis on nonsurgical treatment of patients with chronic periodontitis by means of scaling and root planing (SRP) with or without adjuncts. A panel of experts convened by the American Dental Association Council on Scientific Affairs

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