추천 제품
Quality Level
분석
≥98% (HPLC)
양식
powder
색상
off-white to light tan
solubility
DMSO: ≥20 mg/mL
저장 온도
room temp
SMILES string
OC(=O)COC(=O)Cc1ccccc1Nc2c(Cl)cccc2Cl
InChI
1S/C16H13Cl2NO4/c17-11-5-3-6-12(18)16(11)19-13-7-2-1-4-10(13)8-15(22)23-9-14(20)21/h1-7,19H,8-9H2,(H,20,21)
InChI key
MNIPYSSQXLZQLJ-UHFFFAOYSA-N
유전자 정보
human ... PTGS2(5743)
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관련 카테고리
애플리케이션
Aceclofenac (ACE) has been used as an internal standard in the in vivo blood-brain barrier assay. It has also been used to study the interaction of ACE with bovine serum albumin (BSA) by using spectroscopic techniques in combination with computational methods.
생화학적/생리학적 작용
Aceclofenac is a phenyl acetic acid derivative used for treating symptoms like swelling, tenderness, and stiffness due to muscle-skeletal and bone-related diseases (rheumatoid arthritis, juvenile arthritis, osteoarthritis, and acute gouty arthritis). This compound shows analgesic and antipyretic properties. Aceclofenac suppresses prostaglandin biosynthesis.
Non-steroidal, anti-inflammatory drug (NSAID), with selectivity for COX-2 over COX-1.
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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이미 열람한 고객
K Karthikeyan et al.
AAPS PharmSciTech, 13(1), 143-149 (2011-12-15)
Nonsteroidal anti-inflammatory drugs (NSAIDs) induce gastric injury on long-term usage. This study aims at reducing the side effect of NSAIDs by encapsulating in zein, an acid-resistant biopolymer. Aceclofenac-loaded zein microspheres were prepared by emulsification and solvent evaporation method. The stability
Kyung Rok Chu et al.
Archives of pharmacal research, 35(7), 1187-1195 (2012-08-07)
This study examined the effects of the particle size of various poorly water-soluble drugs on their dissolution behavior through physicochemical and mathematical analysis. As model drugs, hydrochlorothiazide, aceclofenac, ibuprofen and a discovery candidate were selected. The materials were crystallized using
Erik Legrand
Expert opinion on pharmacotherapy, 5(6), 1347-1357 (2004-05-28)
Aceclofenac (Almirall Prodesfarma SA) is an oral NSAID that is effective in the treatment of painful inflammatory diseases and has been used to treat > 75 million patients worldwide. It has proved as effective as diclofenac, naproxen and piroxicam in
R N Brogden et al.
Drugs, 52(1), 113-124 (1996-07-01)
Aceclofenac is a phenylacetic acid derivative with anti-inflammatory and analgesic properties similar to those of diclofenac. However, preclinical studies suggest that the potential of aceclofenac to cause gastrointestinal damage is less than that of diclofenac. Double-blind comparative trials indicate that
Jhi-Kai Chang et al.
Clinical rheumatology, 32(3), 341-347 (2012-11-30)
This study aimed to determine the safety and efficacy of tramadol 37.5 mg/acetaminophen 325 mg combination tablets (Ultracet®) in patients with ankylosing spondylitis (AS). This was a 12-week, randomized, double-blind, placebo-controlled study. Sixty patients with active AS according to the
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