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Merck
모든 사진(3)

주요 문서

A4529

Sigma-Aldrich

Aprotinin

3-7 TIU/mg solid, lyophilized powder

동의어(들):

BPTI, Bovine pancreatic trypsin inhibitor, Trasylol, Trypsin inhibitor (basic)

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About This Item

실험식(Hill 표기법):
C284H432N84O79S7
CAS Number:
Molecular Weight:
6511.44
EC Number:
MDL number:
UNSPSC 코드:
12352202
NACRES:
NA.54

product name

Aprotinin from bovine lung, lyophilized powder, 3-7 TIU/mg solid

생물학적 소스

bovine lung

Quality Level

형태

lyophilized powder

특이 활성도

3-7 TIU/mg solid

분자량

~6,500

solubility

H2O: >10 mg/mL

UniProt 수납 번호

저장 온도

2-8°C

InChI key

ZPNFWUPYTFPOJU-UHFFFAOYSA-N

유전자 정보

cow ... PTI(404172)

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애플리케이션

Aprotinin is largely used as an inhibitor of trypsin.

생화학적/생리학적 작용

Aprotinin is a competitive serine protease inhibitor that forms stable complexes with and blocks the active sites of enzyme. This binding is reversible, and most aprotinin-protease complexes will dissociate at extreme pH levels >10 or <3. Structurally, Aprotinin is a monomeric globular protein derived from bovine lung that consists of 58 amino acids, arranged in a single polypeptide chain with three crosslinking disulfide bridges.

단위 정의

One Trypsin Inhibitor Unit (TIU) will decrease the activity of two trypsin units by 50%, where one trypsin unit will hydrolyze 1.0 μmole of N-alpha-benzoyl-DL-arginine p-nitroanilide per minute at pH 7.8 and 25°C. Another commonly used unit is the KIU, with 1 TIU = 1,300 KIU.

제조 메모

This product is an affinity purified lyophilized powder purified to remove trace impurities. It has an activity of 3-7 TIU/mg.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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프로토콜

Enzymatic Assay of Aprotinin

자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..

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