A2093

Aspirin

meets USP testing specifications

• 동의어(들): Acetylsalicylic acid, 2-Acetoxybenzoic acid, O-Acetylsalicylic acid, ASA, Aspirin
• Linear Formula: 2-(CH₃CO₂)C₆H₄CO₂H
• CAS Number: 50-78-2
• Molecular Weight: 180.16
• Beilstein: 779271
• EC Number: 200-064-1
• MDL number: MFCD00002430
• UNSPSC 코드: 12352106
• PubChem Substance ID: 24890623
• NACRES: NA.21

속성

• Agency: USP/NF; meets USP testing specifications
• Quality Level: 200
• 형태: powder or crystals
• mp: 134-136 °C (lit.)
• 응용 분야: pharmaceutical (small molecule)
• SMILES string: CC(=O)Oc1ccccc1C(O)=O
• InChI: 1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12)
• InChI key: BSYNRYMUTXBXSQ-UHFFFAOYSA-N
• 유전자 정보: human ... ITGA2B(3674) , PTGS1(5742) , PTGS2(5743)

설명

일반 설명

Aspirin (acetylsalicylic acid) is a nonsteroidal anti-inflammatory drug. It occurs as white crystalline powder and is derived from salicylic acid.

애플리케이션

Aspirin has been used:

• as a stabilizer for blood during 13,14-dihydro-15-keto-prostaglandin F2α (PGFM) measurement
• to evaluate cell viability of BV-2 microglial cell line
• in morphogenesis assay

생화학적/생리학적 작용

Aspirin is an analgesic and antipyretic agent used in the treatment of fever and pain as in arthritis. It is also associated with cardiovascular diseases.

Blocks the production of prostaglandins by inhibiting cyclooxygenase (prostaglandin H synthase), with greater selectivity toward the COX-1 isoform. The antithrombotic effect is due to the inhibition of COX-1 in platelets that blocks thromboxane production and platelet aggregation. Chemopreventive against colorectal and other solid tumors.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302
• 예방조치 성명서: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): 482.0 °F
• Flash Point (°C): 250 °C
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Faceshields, Gloves