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Merck
모든 사진(2)

주요 문서

A2074

Sigma-Aldrich

Monoclonal Anti-Rabbit Immunoglobulins–Peroxidase antibody produced in mouse

clone RG-16, purified immunoglobulin, lyophilized powder

동의어(들):

Monoclonal Anti-Rabbit Immunoglobulins (IgG, IgA, IgM)

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.46

생물학적 소스

mouse

Quality Level

결합

peroxidase conjugate

항체 형태

purified immunoglobulin

항체 생산 유형

secondary antibodies

클론

RG-16, monoclonal

양식

lyophilized powder

종 반응성

rabbit

반응하면 안 됨

pig, chicken, bovine, horse, human, guinea pig, turkey, rat, canine, goat, feline, sheep

포장

vial of 0.5 mL

기술

direct ELISA: 1:30,000
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100 using human tissue
western blot (chemiluminescent): 1:160,000

동형

IgG1

저장 온도

2-8°C

타겟 번역 후 변형

unmodified

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관련 카테고리

일반 설명

Monoclonal Anti-Rabbit Immunoglobulins (mouse IgG1 isotype) is derived from the RG-16 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from mice immunized with rabbit IgG. Immunoglobulins (Igs) belongs to the immunoglobulin super-family. There are five different types of Immunoglobulins. Each immunoglobulin has two heavy (H) and two light (L) chains held together by disulfide linkages. Each light comprises one variable N-terminal region and a constant C-terminal region. Heavy chain has one variable N-terminal region and three or four constant (CH1-CH4) C-terminal region. IgG is abundant immunoglobulin in human serum. The four classes of IgG can be IgG1, IgG2, IgG3, and IgG4.
Reacts with an epitope on the heavy chain of rabbit IgG, IgA and IgM, which is sensitive to reduction. No cross-reactivity with human IgG, IgA and IgM.

특이성

Binds only rabbit Igs. Does not react with reduced rabbit Igs.

애플리케이션

Monoclonal Anti-Rabbit Immunoglobulins-Peroxidase antibody produced in mouse has been used in:
  • western blotting
  • immunoblotting
  • immunoprecipitation
  • enzyme linked immunosorbent assay (ELISA)
  • immunohistochemistry

Mouse monoclonal anti-rabbit immunoglobulins have been used for western blot assays at a dilution of 1:1000 using bovine trabecular meshwork cell lysates. The antibody can also be used for immunohistochemistry assays (1:100, using human tissue).
The mouse monoclonal anti-Rabbit IgG (heavy chain-specific) peroxidase conjugated antibody can be used as a secondary antibody for western blot analysis of protein preps from E. coli cultures at a concentration of 1:10000 diluted in PBSt for 1 hour at room temperature.

물리적 형태

Lyophilized from 0.01 M sodium phosphate buffer, pH 7.4, containing 1% bovine serum albumin and 0.05% MIT

제조 메모

Prepared by the two-step glutaraldehyde method described by Avrameas, S., et al., Scand. J. Immunol., 8, Suppl. 7, 7 (1978).

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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픽토그램

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신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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