46123
1-(Ethoxycarbonylmethyl)-6-methoxyquinolinium bromide
suitable for fluorescence, ≥97.0% (TLC)
동의어(들):
(6-Methoxyquinolinio)acetic acid ethyl ester bromide, MQAE
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모든 사진(1)
About This Item
실험식(Hill 표기법):
C14H16BrNO3
CAS Number:
Molecular Weight:
326.19
MDL number:
UNSPSC 코드:
12352106
PubChem Substance ID:
NACRES:
NA.32
추천 제품
Quality Level
분석
≥97.0% (TLC)
양식
solid
mp
177-179 °C (lit.)
solubility
DMSO: soluble
H2O: soluble
methanol: soluble
형광
λex 350 nm; λem 460 nm in 0.1 M borate pH 8.0 (quenching with Cl-)
적합성
suitable for fluorescence
저장 온도
2-8°C
SMILES string
[Br-].CCOC(=O)C[n+]1cccc2cc(OC)ccc12
InChI
1S/C14H16NO3.BrH/c1-3-18-14(16)10-15-8-4-5-11-9-12(17-2)6-7-13(11)15;/h4-9H,3,10H2,1-2H3;1H/q+1;/p-1
InChI key
DSLLHVISNOIYHR-UHFFFAOYSA-M
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애플리케이션
1-(Ethoxycarbonylmethyl)-6-methoxyquinolinium bromide, a fluorescent chloride indicator dye, may be used to measure intracellular and extracellular chloride concentrations.
기타 정보
Improved chloride probe. Used to measure chloride transport in liposome membranes
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
표적 기관
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
dust mask type N95 (US), Eyeshields, Gloves
Tamer Coskun et al.
American journal of physiology. Gastrointestinal and liver physiology, 283(5), G1147-G1155 (2002-10-17)
Gastric secretion of hydrochloric acid requires protons and chloride, yet the mechanisms and regulation of gastric chloride secretion remain unclear. We developed an in vivo technique to simultaneously measure acid/base and chloride secretion into the gastric lumen of anesthetized rats.
Danielle Collins et al.
Annals of surgery, 254(6), 957-963 (2011-05-13)
Mucosal hypoxia is a common endpoint for many pathological processes including ischemic colitis, colonic obstruction and anastomotic failure. Previous studies suggest that hypoxia modulates colonic mucosal function through inhibition of chloride secretion. However, the molecular mechanisms underlying this observation are
A S Verkman et al.
Analytical biochemistry, 178(2), 355-361 (1989-05-01)
A class of N-substituted quinoline compounds has been introduced recently for the fluorescence measurement of Cl concentration in biological preparations. The most Cl-sensitive compound was 6-methoxy-N-[3-sulfopropyl] quinolinium with peak excitation and emission wavelengths of 350 and 442 nm and a
Verena Keitel et al.
Hepatology (Baltimore, Md.), 50(3), 861-870 (2009-07-08)
TGR5 (Gpbar-1) is a plasma membrane-bound, G protein-coupled receptor for bile acids. TGR5 messenger RNA (mRNA) has been detected in many tissues, including rat cholangiocytes and mouse gallbladder. A role for TGR5 in gallstone formation has been suggested, because TGR5
Héctor I Rocha-González et al.
Journal of neurophysiology, 100(1), 169-184 (2008-04-04)
Adult primary afferent neurons are depolarized by GABA throughout their entire surface, including their somata located in dorsal root ganglia (DRG). Primary afferent depolarization (PAD) mediated by GABA released from spinal interneurons determines presynaptic inhibition, a key mechanism in somatosensory
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