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Merck
모든 사진(1)

Key Documents

453R-1

Sigma-Aldrich

p53 (SP5) Rabbit Monoclonal Antibody

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모든 사진(1)

About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

100
500

결합

unconjugated

항체 형태

culture supernatant

항체 생산 유형

primary antibodies

클론

SP5, monoclonal

설명

For In Vitro Diagnostic Use in Select Regions (See Chart)

형태

buffered aqueous solution

종 반응성

human

포장

vial of 0.1 mL concentrate (453R-14)
vial of 0.5 mL concentrate (453R-15)
bottle of 1.0 mL predilute (453R-17)
vial of 1.0 mL concentrate (453R-16)
bottle of 7.0 mL predilute (453R-18)

제조업체/상표

Cell Marque™

기술

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100

동형

IgG1

제어

colon carcinoma

배송 상태

wet ice

저장 온도

2-8°C

시각화

nuclear

유전자 정보

human ... TP53(7157)

일반 설명

Anti-p53 tumor suppressor protein antibody recognizes a 53 kDa phosphoprotein, identified as p53 suppressor gene product. It reacts with the mutant as well as wild type p53, although significant accumulation of the mutant form of p53 protein due to longer half-life half-life is the basis for the test using the IHC technique. Quantitation of nuclear staining with this antibody has been shown to be a factor in breast carcinoma, lung carcinoma, colorectalcarcinoma, urothelial carcinoma, and ependymoma. p53 positivity has also been used to differentiate uterine serous carcinoma from endometrioid carcinoma as well as to detect intratubular germ cell neoplasia.

결합

p53 Positive Control Slides, Product No. 453S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

물리적 형태

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

제조 메모

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

기타 정보

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

법적 정보

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Diagnostic Immunohistochemistry: Theranostic and Genomic Applications (2006)
A Korshunov et al.
Journal of the neurological sciences, 177(1), 72-82 (2000-09-01)
Intracranial ependymomas are the third most common primary brain tumor in children. Although clinical and histological criteria for ependymoma prognosis are recognized, studies have reported contradictory results. Prognostic significance based on immunohistochemistry of ependymomas has been reported in a few
B E Moore et al.
Applied immunohistochemistry & molecular morphology : AIMM, 9(3), 203-206 (2001-09-15)
Intratubular germ cell neoplasia, unclassified (IGCNU) is a precursor of germ cell tumors (GCT) of the testis. In routine histologic sections, neoplastic intratubular germ cells may be very few and easily overlooked. The aim of this study is two-fold: to
C Midulla et al.
Anticancer research, 19(5B), 4033-4037 (2000-01-11)
The different clinical evolution of breast cancer with similar pathological characteristics prompted the authors to investigate the prognostic significance of different biological markers. Seventy-one primary breast carcinoma specimens obtained by mastectomy or quadrantectomy were examined for the determination of the
F A Mauri et al.
International journal of oncology, 15(6), 1137-1147 (1999-11-24)
Steroid receptor analysis is the only widely accepted prognostic/predictive marker in breast cancer (BC) treatment. In the present study we evaluated the prognostic role of ER/PgR with p53 and Bcl2, in a series of 277 BC (153 pN1/2, 122 pNO
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