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Merck
모든 사진(1)

주요 문서

214906

Sigma-Aldrich

Hypophosphorous acid solution

50 wt. % in H2O

동의어(들):

Phosphinic acid

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About This Item

Linear Formula:
H3PO2
CAS Number:
Molecular Weight:
66.00
MDL number:
UNSPSC 코드:
12352106
PubChem Substance ID:
NACRES:
NA.21

vapor pressure

<17 mmHg ( 20 °C)

Quality Level

양식

liquid

농도

48-52% in NaOH (titration)
50 wt. % in H2O

pH

1 (20 °C, 500 g/L)

density

1.206 g/mL at 25 °C

SMILES string

O[PH2]=O

InChI

1S/H3O2P/c1-3-2/h3H2,(H,1,2)

InChI key

ACVYVLVWPXVTIT-UHFFFAOYSA-N

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일반 설명

H3PO2, a monobasic oxyacid, is also referred to as phosphinic acid. H3PO2 participates as a reducing agent for the conversion of aromatic and aliphatic diselenides to the corresponding selenols.
It undergoes oxidation in the presence of Ce(IV) and a strong acid to afford cerium(IV) hypophosphite complex ions.

애플리케이션


  • Synthesis of Aminobisphosphinates through a Cascade Reaction between Hypophosphorous Acid and Bis(trimethylsilyl)imidates Mediated by ZnI(2).: This research presents a novel method for synthesizing aminobisphosphinates, utilizing hypophosphorous acid in a zinc iodide-mediated cascade reaction, which could be relevant in the development of new chemical entities in medicinal chemistry (Ayadi et al., 2023).

  • Facile Synthesis of Liquid Crystal Dimers Bridged with a Phosphonic Group.: This study explores the use of hypophosphorous acid in the synthesis of phosphonic group-bridged liquid crystal dimers, offering potential advancements in materials science and display technologies (Wang et al., 2022).

  • Oxidation of Hypophosphorous Acid by a Ruthenium(VI) Nitrido Complex in Aqueous Acidic Solution. Evidence for a Proton-Coupled N-Atom Transfer Mechanism.: Investigates the mechanistic details of hypophosphorous acid oxidation by a ruthenium complex, shedding light on reaction pathways important in catalysis and synthesis (Li et al., 2022).

  • Solution-processed Ge(ii)-based chalcogenide thin films with tunable bandgaps for photovoltaics.: Discusses the application of hypophosphorous acid in the development of germanium-based chalcogenide thin films, contributing to advancements in photovoltaic materials (Hu et al., 2022).

  • One-Pot Synthesis and in Silico Molecular Docking Studies of Arylselanyl Hydrazides as Potential Antituberculosis Agents.: Utilizes hypophosphorous acid in the one-pot synthesis of arylselanyl hydrazides, evaluated for their potential as antituberculosis agents through molecular docking studies (Borges et al., 2022).

픽토그램

Corrosion

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B

Storage Class Code

8B - Non-combustible corrosive hazardous materials

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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문서 라이브러리 방문

The Kinetics and Mechanism of the Oxidation of Hypophosphorous Acid by Cerium (IV) in Perchloric Acid Solution.
Carroll RL and Thomas LB.
Journal of the American Chemical Society, 88(7), 1376-1381 (1996)
Hypophosphorous acid mediated dehalogenation in water.
Jang DO.
Tetrahedron Letters, 37(30), 5367-5368 (1996)
Jayesh Cherusseri et al.
Nanoscale, 12(18), 10072-10081 (2020-04-30)
We present a simple and facile method to synthesize nanoplatelets of 2D Ruddlesden-Popper (RP) perovskites of the type (CH3(CH2)3NH3)2(CH3NH3)Pb2I7 where n = 2. The 2D RP nanoplatelets are synthesized from bulk 2D RP crystals via a reflux pre-treatment mediated-ultrasonication method.
Kai Wang et al.
ACS nano, 12(5), 4919-4929 (2018-04-24)
The robust material stability of the quasi-two-dimensional (quasi-2D) metal halide perovskites has opened the possibility for their usage instead of three-dimensional (3D) perovskites. Further, devices based on large area single crystal membranes have shown increasing promise for photoelectronic applications. However
Hypophosphorous Acid, a Novel Reagent for the Reduction of Diselenides and the Selenol-Catalyzed Reduction of Disulfides1,2.
Gunther WHH.
The Journal of Organic Chemistry, 31(4), 1202-1205 (1966)

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