F6377

Fluorescein sodium salt

used as fluorescent tracer

• 동의어(들): Acid Yellow 73, D&C;Yellow No. 8, NaFl, NaFluo, Sodium fluorescein, Uranine
• 실험식(Hill 표기법): C₂₀H₁₀Na₂O₅
• CAS Number: 518-47-8
• Molecular Weight: 376.27
• 색상 지수 번호: 45350
• Beilstein: 3833041
• EC Number: 208-253-0
• MDL number: MFCD00167039
• UNSPSC 코드: 12171500
• PubChem Substance ID: 24894907
• NACRES: NA.47

속성

• Quality Level: 200
• 양식: powder
• 색상: orange to brown
• pH: 8.3 (20 °C, 10 g/L)
• mp: >300 °C
• solubility: H₂O: 1 mg/mL
• density: 0.78 g/cm³ at 29.6 °C (85.3 °F at 699.7 hPa)
• 형광: λ_ex 460 nm; λ_em 515 nm(lit.)
• 응용 분야: diagnostic assay manufacturing; hematology; histology
• 저장 온도: room temp
• SMILES string: [Na+].[Na+].[O-]c1ccc2c(Oc3cc([O-])ccc3C24OC(=O)c5ccccc45)c1
• InChI: 1S/C20H12O5.2Na/c21-11-5-7-15-17(9-11)24-18-10-12(22)6-8-16(18)20(15)14-4-2-1-3-13(14)19(23)25-20;;/h1-10,21-22H;;/q;2*+1/p-2
• InChI key: RGPLGPBQJOQFJS-UHFFFAOYSA-L

설명

일반 설명

Fluorescein is a xanthene dye and is a common labeling agent in biology.

애플리케이션

Fluorescein sodium salt has been used as a solute to study microvessel permeability. It has been used as a test molecule to study blood barrier penetration.

Water soluble fluorescent dye used in permeability and vascular perfusion studies due to its small molecular radius. Sodium fluorescein is used as a fluorescent tracer to study blood-brain barrier (BBB) and blood-spinal cord barrier (BSCB) permeability in rodent models. The dye was used as a probe substrate in the study of organic anion transporting polypeptide (OATP) mediated drug transport in hepatocytes. Sodium fluorescein was also used to monitor in situ solute transportation into bone through fluorescence recovery after photobleaching (FRAP).

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): 423.7 °F - Pensky-Martens closed cup
• Flash Point (°C): 217.6 °C - Pensky-Martens closed cup
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)