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Merck
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Key Documents

PHR1085

Supelco

Homosalate

Pharmaceutical Secondary Standard; Certified Reference Material

동의어(들):

3,3,5-Trimethylcyclohexyl salicylate, 2-Hydroxybenzoic acid 3,3,5-trimethylcyclohexyl ester, Homomenthyl salicylate, Homosalate

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About This Item

실험식(Hill 표기법):
C16H22O3
CAS Number:
Molecular Weight:
262.34
Beilstein:
2731604
EC Number:
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:
NACRES:
NA.24

Grade

certified reference material
pharmaceutical secondary standard

Quality Level

Agency

traceable to USP 1311408

API family

homosalate

CofA

current certificate can be downloaded

기술

HPLC: suitable
gas chromatography (GC): suitable

응용 분야

cleaning products
cosmetics
environmental
food and beverages
personal care
pharmaceutical (small molecule)

형식

neat

저장 온도

2-30°C

SMILES string

CC1CC(CC(C)(C)C1)OC(=O)c2ccccc2O

InChI

1S/C16H22O3/c1-11-8-12(10-16(2,3)9-11)19-15(18)13-6-4-5-7-14(13)17/h4-7,11-12,17H,8-10H2,1-3H3

InChI key

WSSJONWNBBTCMG-UHFFFAOYSA-N

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일반 설명

Homosalate is a UV filter that protects the skin from the harmful effects of UVB (280-315 nm) and UVA II (315-340 nm) radiations. It is widely utilized in make-up, sunscreen and topical formulations.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

애플리케이션

Homosalate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography methods.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

분석 메모

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

기타 정보

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

각주

To see an example of a Certificate of Analysis for this material enter LRAC3174 in the slot below. This is an example certificate only and may not be the lot that you receive.

관련 제품

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point (°F)

339.4 °F - closed cup

Flash Point (°C)

170.8 °C - closed cup


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문서 라이브러리 방문

Rapid analysis of ultraviolet filters using dispersive liquid-liquid microextraction coupled to headspace gas chromatography and mass spectrometry
Pierson SA, et al.
Journal of Separation Science, 41(15), 3081-3088 (2018)
Homosalate
USP42-NF37: United States Pharmacopeia and National Formulary
United States Pharmacopeia/National Formulary, 37(2), 2163-2163 (2013)
Supercritical fluid extraction and high performance liquid chromatography determination of homosalate in lipsticks
Salvador A, et al.
Chromatographia, 54(11-12), 795-797 (2001)
Benjamin Choquenet et al.
Journal of natural products, 71(6), 1117-1118 (2008-06-03)
Given that flavonoids are known for their ultraviolet (UV)B photoprotective properties in plants that contain them, we chose to study quercetin (1) and rutin (2) as agents that could potentially be used in sunscreen products. These two substances proved to
Yufeng Zhang et al.
Journal of chromatography. A, 1271(1), 56-61 (2012-12-15)
In the present study, a rapid, highly efficient and environmentally friendly sample preparation method named temperature-controlled ionic liquid dispersive liquid-phase microextraction (TC-IL-DLPME), followed by high performance liquid chromatography (HPLC) was developed for the extraction, preconcentration and determination of four benzophenone-type

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