PHL82325

Veratridine

phyproof^® Reference Substance

• 동의어(들): 3-Veratroylveracevine, Veracevine veratrate
• 실험식(Hill 표기법): C₃₆H₅₁NO₁₁
• CAS Number: 71-62-5
• Molecular Weight: 673.79
• Beilstein: 78875
• EC Number: 200-758-4
• MDL number: MFCD00082515
• UNSPSC 코드: 41116107

속성

• Grade: primary reference standard
• 제품 라인: phyproof^® Reference Substance
• 분석: ≥95.0% (HPLC)
• 제조업체/상표: PhytoLab
• 응용 분야: food and beverages
• 형식: neat
• 저장 온도: −20°C
• SMILES string: COc1ccc(cc1OC)C(=O)OC2CC[C@@]3(C)C4CCC5[C@]6(O)C[C@H](O)[C@@]7(O)C(CN8CC(C)CCC8[C@@]7(C)O)[C@]6(O)C[C@]35O[C@]24O
• InChI: 1S/C36H51NO11/c1-19-6-11-26-31(3,40)35(43)25(17-37(26)16-19)33(42)18-34-24(32(33,41)15-27(35)38)10-9-23-30(34,2)13-12-28(36(23,44)48-34)47-29(39)20-7-8-21(45-4)22(14-20)46-5/h7-8,14,19,23-28,38,40-44H,6,9-13,15-18H2,1-5H3/t19?,23?,24?,25?,26?,27-,28?,30-,31+,32+,33+,34+,35-,36-/m0/s1
• InChI key: FVECELJHCSPHKY-FCSYLLAHSA-N

설명

일반 설명

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

생화학적/생리학적 작용

Opens voltage-dependent Na⁺ channels and prevents their inactivation. This, in turn, opens voltage-activated calcium channels, thus increasing intracellular calcium content and inducing neurotransmitter release. Alkaloid neurotoxin which depolarizes excitable tissue; used to increase membrane sodium permeability. Veratridine is cytotoxic to chromaffin cells in vitro.

법적 정보

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

안전성 정보

• 픽토그램: GHS06
• 신호어: Danger
• 유해 및 위험 성명서: H300 + H310 + H330 - H315 - H319 - H335
• 예방조치 성명서: P260 - P262 - P280 - P301 + P310 + P330 - P302 + P352 + P310 - P304 + P340 + P310 - P403 + P233
• Hazard Classifications: Acute Tox. 1 Dermal - Acute Tox. 1 Inhalation - Acute Tox. 1 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3