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Merck
모든 사진(7)

주요 문서

P5631

Sigma-Aldrich

o-Cresolphthalein Complexone

powder

동의어(들):

o-Cresolphthalein-3′,3′′-bis-methyleneiminodiacetic acid, o-Cresolphthalexon, Metal phthalein, Phthalein purple, Xylenylphthalein-bisiminodiacetic acid

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About This Item

실험식(Hill 표기법):
C32H32N2O12
CAS Number:
Molecular Weight:
636.60
Beilstein:
381994
EC Number:
MDL number:
UNSPSC 코드:
12171500
PubChem Substance ID:
NACRES:
NA.47

양식

powder

Quality Level

기술

titration: suitable

색상

white to off-white

mp

181-185 °C (dec.) (lit.)

solubility

methanol: 1 mg/mL

적합성

suitable for determination of calcium

응용 분야

diagnostic assay manufacturing
hematology
histology

저장 온도

room temp

SMILES string

Cc1cc(cc(CN(CC(O)=O)CC(O)=O)c1O)C2(OC(=O)c3ccccc23)c4cc(C)c(O)c(CN(CC(O)=O)CC(O)=O)c4

InChI

1S/C32H32N2O12/c1-17-7-21(9-19(29(17)43)11-33(13-25(35)36)14-26(37)38)32(24-6-4-3-5-23(24)31(45)46-32)22-8-18(2)30(44)20(10-22)12-34(15-27(39)40)16-28(41)42/h3-10,43-44H,11-16H2,1-2H3,(H,35,36)(H,37,38)(H,39,40)(H,41,42)

InChI key

IYZPEGVSBUNMBE-UHFFFAOYSA-N

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일반 설명

o-Cresolphthalein Complexone is a pH indicator dye commonly used for the calorimetric determination of calcium in serum.

애플리케이션

o-Cresolphthalein Complexone has been used in the estimation of calcium in serum samples based on the reaction of Ca2+ with o-cresolphthalein complexone in an alkaline solution.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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문서 라이브러리 방문

J Toffaletti et al.
Clinical chemistry, 26(11), 1562-1565 (1980-10-01)
We adapted a method for dialyzable calcium from fluorometric detection by use of calcein to a more specific spectrophotometric determination with cresolphthalein complexone. The reagents are available commercially and perform satisfactorily with respect to noise level, drift, stability, and sensitivity.
Improved determination of serum calcium with 2-cresolphthalein complexone.
K Lorentz
Clinica chimica acta; international journal of clinical chemistry, 126(3), 327-334 (1982-12-23)
Improved linearity of the calcium-cresolphthalein complexone reaction with sodium acetate.
D M Cowley et al.
Clinical chemistry, 32(5), 894-895 (1986-05-01)
C M Corns et al.
Annals of clinical biochemistry, 24 ( Pt 4), 345-351 (1987-07-01)
The reasons for the non-linearity of the standard curve for the calcium-cresolphthalein complexone reaction have been investigated. Calcium forms both 1:1 and 2:1 complexes with cresolphthalein complexone; at low calcium concentrations the 1:1 complex predominates and causes non-linearity. At high
Sandra F Williams et al.
Mayo Clinic proceedings, 80(12), 1655-1657 (2005-12-14)
Severe hypocalcemia may require prompt intervention to avoid life-threatening consequences. We report a case in which a 78-year-old man had a critically low serum calcium level measured with use of standard colorimetric assay after gadodiamide administration during magnetic resonance angiography.

프로토콜

Suitability for the Qualitative Determination of Calcium with Phthalein Purple (O-Cresophthalein Complexone) using Stannous Chloride

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